Trimebutine EP Impurity B/Trimethoprim EP Impurity J CAS 118-41-2
| CAS No. | 118-41-2 |
| Molecular Formula | C10H12O5 |
| Molecular Weight | 212.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Trimebutine EP Impurity B/Trimethoprim EP Impurity J (C10H12O5) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Trimebutine EP Impurity B/Trimethoprim EP Impurity J (CAS 118-41-2, C10H12O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Trimebutine EP Impurity B/Trimethoprim EP Impurity J meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H12O5 |
| Molecular Weight | 212.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Trimebutine Standards
- Trimebutine Impurity 22 (CAS CATO-C4X-185822)
- Trimebutine Maleate Impurity 1 (CAS 5612-61-3)
- Trimebutine EP Impurity A (CAS 39068-94-5)
- Trimebutine Impurity 24 (CAS 16623-25-9)
- Trimebutine Impurity 11 (CAS CATO-C4X-185811)
- Trimebutine Impurity 3 (CAS 78483-47-3)
- Trimebutine Impurity 21 (CAS CATO-C4X-185821)
- Trimebutine Impurity 16 (CAS CATO-C4X-185816)
Recommended Standards
- N-Nitroso Epinephrine (CAS 3006789-99-4)
- (1S,2S)-2-Amino-1-(4-nitrophenyl)propane-1,3-diol (CAS 2964-48-9)
- Trimetazidine Impurity 20 (CAS 573-11-5)
- Finerenone Impurity 205 (CAS 890705-78-9)
- Tocopherol Impurity 33 (CAS CATO-C4X-119533)
- Metaraminol Impurity 59 (CAS CATO-C4X-225259)
- Azacitidine Impurity 83 (CAS CATO-C4X-138883)
- 1,3,5,7-Tetramethyladamantane (CAS 1687-36-1)
- 5-Amino-4-methyl-2-nitrophenol (CAS 2055119-24-7)
- 2-Amino-3,4,5,6-tetrachlorobenzoic acid (CAS 6923-69-9)
- 2-Cyano-4-(trifluoromethyl)phenylboronic Acid Pinacol Ester (CAS 1073355-21-1)
- Ethyl 1-cyclopropyl-3-methyl-1H-pyrazole-5-carboxylate (CAS 844872-73-7)
- 2-(2,3-Dimethylthiomorpholino)but-3-enoic acid (CAS 1694531-38-8)
- Heme iron polypeptide(Hematin) (CAS 14875-96-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com