Trimetazidine Impurity 20 CAS 573-11-5
| CAS No. | 573-11-5 |
| Molecular Formula | C10H12O5 |
| Molecular Weight | 212.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Trimetazidine Impurity 20 (CAS 573-11-5, C10H12O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Trimetazidine Impurity 20 (C10H12O5) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 212.20 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Trimetazidine Impurity 20 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H12O5 |
| Molecular Weight | 212.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Trimetazidine Standards
- Trimetazidine Impurity 5 (CAS 1133-49-9)
- Trimetazidine EP Impurity D (CAS 71989-96-3)
- Trimetazidine Dihydrochloride EP Impurity C (CAS 2103-57-3)
- Trimetazidine Impurity 22 (CAS 86-81-7)
- Trimetazidine impurity 34 (CAS CATO-C4X-180334)
- Trimetazidine Impurity 21 (CAS 69471-05-2)
- Trimetazidine Impurity 11 (CAS CATO-C4X-180311)
- Trimetazidine Impurity 12 (CAS 169506-15-4)
Recommended Standards
- Norepinephrine Impurity 100 (CAS CATO-C4X-1514100)
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- Trimebutine EP Impurity B/Trimethoprim EP Impurity J (CAS 118-41-2)
- Thioctic acid Impurity 79 (CAS 105986-59-2)
- Dotinurad Impurity 113 (CAS CATO-C4X-2494113)
- Ticagrelor Impurity 190 (CAS 2880337-24-4)
- Ethyl 8-fluoro-4-hydroxy-6-methylquinoline-3-carboxylate (CAS 228728-22-1)
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- 4-Methyl-2-((2-(piperidin-2-yl)ethyl)thio)pyrimidine (CAS 1249572-20-0)
- 3-Chloro-6-chloromethylpyridazine (CAS 120276-59-7)
- Methyl 2,5-dichloroquinoline-4-carboxylate (CAS 62482-34-2)
- Macrocyclic Peptide flaviviridae Viruses InhibitorDISCONTINUED (CAS 1510840-70-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com