2-(4-Hydroxypiperidin-1-yl)acetic acid hydrochloride CAS 1181544-77-3
| CAS No. | 1181544-77-3 |
| Molecular Formula | C7H13NO3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-(4-Hydroxypiperidin-1-yl)acetic acid hydrochloride (C7H13NO3HCl) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-(4-Hydroxypiperidin-1-yl)acetic acid hydrochloride (CAS 1181544-77-3), molecular formula C7H13NO3HCl and molecular weight 195.64 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(4-Hydroxypiperidin-1-yl)acetic acid hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H13NO3 HCl |
| Molecular Weight | 195.64 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Hydroxypiperidin Standards
- 2-[2-(4-Hydroxypiperidin-1-yl)-ethyl]isoindole-1,3-dione (CAS 101620-61-5)
- 4-[(4-hydroxypiperidin-1-yl)sulfonyl]benzoic acid (CAS 1016503-99-3)
- 4-[(4-hydroxypiperidin-1-yl)sulfonyl]benzonitrile (CAS 1016887-02-7)
- 6-(4-Hydroxypiperidin-1-yl)nicotinonitrile (CAS 1017034-18-2)
- 2-(4-Hydroxypiperidin-1-yl)-2-phenylacetonitrile (CAS 1018437-11-0)
- 5-Ethyl-4-hydroxypiperidin-2-one (CAS 102014-75-5)
- (R)-5-Hydroxypiperidin-2-one (CAS 102774-92-5)
- 2-(4-Hydroxypiperidin-1-yl)-N-(1-(thiophen-2-yl)ethyl)acetamide (CAS 1030765-44-6)
Recommended Standards
- 6-Methoxy-5-methyl-1,2,3,4-tetrahydronaphthalene (CAS 1758-21-0)
- 5-(Cyclopropylmethoxy)-6-nitrobenzo[d][1,3]dioxole (CAS 1706446-05-0)
- 1-(2,5-dimethoxyphenyl)-1,3-diazinan-2-one (CAS 1140241-93-5)
- (3S,6S)-N-((1H-1,2,3-Triazol-5-yl)methyl)-3-((2S,3S)-2-(2-(benzo[b]thiophen-3-yl)acetamido)-3-methylpentanamido)-4-oxo-1,2,3,4,6,7-hexahydroazepino[3,2,1-hi]indole-6-carboxamide (CAS 498555-58-1)
- 3-[(3-bromophenyl)methyl]pyrrolidine-3-carboxylic acid hydrochloride (CAS 1354963-41-9)
- 4-(4-Methylbenzoyl)tetrahydro-2H-pyran-4-carbonitrile (CAS 1403564-77-1)
- Carteolol impurity 36 (CAS CATO-C4X-228736)
- 6-(Tert-butyl)-2-((pyridin-4-ylmethyl)thio)-4-(thiophen-2-yl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile (CAS 354556-51-7)
- 4-Oxo-N-(2-(pyrimidin-5-yl)ethyl)-4H-chromene-2-carboxamide (CAS 2034445-76-4)
- Semaglutide impurity 101 (CAS CATO-C4X-2226101)
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