Carteolol impurity 36 CAS CATO-C4X-228736
| CAS No. | CATO-C4X-228736 |
| Molecular Formula | C12H12BrNO3 |
| Molecular Weight | 298.13 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Carteolol impurity 36 (CAS CATO-C4X-228736, C12H12BrNO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C12H12BrNO3, Carteolol impurity 36 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 298.13 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H12BrNO3 |
| Molecular Weight | 298.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Carteolol Standards
- Carteolol Impurity 35 (CAS CATO-C4X-228735)
- Carteolol Impurity 15 (CAS CATO-C4X-228715)
- Carteolol Impurity 17 (CAS 51781-06-7)
- Carteolol EP Impurity H (CAS 62330-84-1)
- Carteolol Impurity 38 (CAS CATO-C4X-228738)
- Carteolol Impurity 40 (CAS CATO-C4X-228740)
- Carteolol Impurity 32 (CAS CATO-C4X-228732)
- Carteolol Impurity 34 (CAS CATO-C4X-228734)
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