Ethyl 2,2-difluoro-3-hydroxy-3-(thiophen-2-yl)propanoate CAS 118460-42-7
| CAS No. | 118460-42-7 |
| Molecular Formula | C9H10F2O3S |
| Molecular Weight | 236.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 236.24 g/mol gives Ethyl 2,2-difluoro-3-hydroxy-3-(thiophen-2-yl)propanoate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Ethyl 2,2-difluoro-3-hydroxy-3-(thiophen-2-yl)propanoate (CAS 118460-42-7), molecular formula C9H10F2O3S and molecular weight 236.24 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Ethyl 2,2-difluoro-3-hydroxy-3-(thiophen-2-yl)propanoate (C9H10F2O3S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H10F2O3S |
| Molecular Weight | 236.24 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
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