2,2-Difluoro-1-(6-methoxynaphthalen-2-yl)ethanone CAS 1352215-91-8

Purity 97%+In StockPharmaceutical Standards
CAS No.1352215-91-8
Molecular FormulaC13H10F2O2
Molecular Weight236.21 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2,2-Difluoro-1-(6-methoxynaphthalen-2-yl)ethanone CAS 1352215-91-8 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 236.21 g/mol gives 2,2-Difluoro-1-(6-methoxynaphthalen-2-yl)ethanone distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2,2-Difluoro-1-(6-methoxynaphthalen-2-yl)ethanone (CAS 1352215-91-8), molecular formula C13H10F2O2 and molecular weight 236.21 g/mol, is a CATO reference standard with documented purity and traceability.

2,2-Difluoro-1-(6-methoxynaphthalen-2-yl)ethanone (C13H10F2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC13H10F2O2
Molecular Weight236.21 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentF-containing

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