4-(Difluoromethoxy)-3-methoxyaniline hydrochloride CAS 1185012-61-6
| CAS No. | 1185012-61-6 |
| Molecular Formula | C8H9F2NO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(Difluoromethoxy)-3-methoxyaniline hydrochloride (CAS 1185012-61-6), molecular formula C8H9F2NO2HCl and molecular weight 225.62 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C8H9F2NO2HCl, 4-(Difluoromethoxy)-3-methoxyaniline hydrochloride contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 225.62 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-(Difluoromethoxy)-3-methoxyaniline hydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H9F2NO2 HCl |
| Molecular Weight | 225.62 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Difluoromethoxy Standards
- 2-(2-(Difluoromethoxy)phenyl)ethan-1-ol (CAS 1000533-82-3)
- 4-(Difluoromethoxy)-2-iodoaniline (CAS 1000801-26-2)
- 3-(4-(Difluoromethoxy)phenyl)propanoic acid (CAS 1000932-18-2)
- 4-(Difluoromethoxy)-2-fluoroaniline (CAS 1003865-65-3)
- (4-(Difluoromethoxy)-2-fluorophenyl)boronic acid (CAS 1004775-34-1)
- 4,6-Bis(difluoromethoxy)-2-(methylthio)pyrimidine (CAS 100478-25-9)
- 1-(3-(Difluoromethoxy)phenyl)-3-(1,5-dimethyl-1H-pyrazol-4-yl)prop-2-en-1-one (CAS 1005647-45-9)
- Methyl 6-(4-(difluoromethoxy)phenyl)-3-methylisoxazolo[5,4-b]pyridine-4-carboxylate (CAS 1011396-51-2)
Recommended Standards
- Benzyl 2-((2-amino-N-ethylacetamido)methyl)piperidine-1-carboxylate (CAS 1353977-35-1)
- Methyl 4-Dibenzofurancarboxylate (CAS 92151-89-8)
- (3-Methoxy-2,6-dimethylphenyl)methanamine (CAS 1260762-93-3)
- 3-Ethyl-1-methyl-1H-pyrazole-5-carbohydrazide (CAS 198757-17-4)
- (S)-2-((((S)-3-(4-Chlorophenyl)-4-phenyl-4,5-dihydro-1H-pyrazol-1-yl)(4-chlorophenylsulfonamido)methylene)amino)-3-methylbutanamide (CAS 1392116-14-1)
- 4-Fluoro-N-(2-(methylsulfonamido)ethyl)benzamide (CAS 890868-99-2)
- Abiraterone Impurity 32 (CAS 2283-82-1)
- 6-Chloro-2-methyl-3,4'-bipyridine (CAS 88976-11-8)
- 4-[5-Methyl-4-(4-pyridinylmethyl)-4H-1,2,4-triazol-3-yl]-1-phenyl-1H-pyrazol-5-amine (CAS 956193-98-9)
- Semaglutide impurity 60 (CAS CATO-C4X-222660)
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