Abiraterone Impurity 32 CAS 2283-82-1
| CAS No. | 2283-82-1 |
| Molecular Formula | C19H28O2 |
| Molecular Weight | 288.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Abiraterone Impurity 32 (C19H28O2) contains a steroid core, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a process- or degradation-related impurity, Abiraterone Impurity 32 (CAS 2283-82-1, C19H28O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H28O2 |
| Molecular Weight | 288.42 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Abiraterone Standards
- Abiraterone Impurity 34 (CAS 571-44-8)
- Abiraterone Impurity 24 (CAS 90468-14-7)
- Abiraterone Impurity 56 (CAS 500019-37-4)
- Abiraterone Impurity 57 (CAS 62509-26-6)
- Abiraterone Impurity 80 (CAS CATO-C4X-107080)
- Abiraterone Impurity 48 (CAS CATO-C4X-107048)
- Abiraterone Impurity 81 (CAS 2118-31-2)
- Abiraterone Impurity 9 (CAS 566-19-8)
Recommended Standards
- Normethisterone (CAS 514-61-4)
- (8R,9S,10R,13S,14S,17S)-17-hydroxy-10,13-dimethyl-4,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one 5-Androsten-17beta-ol-3-one 571-25-5 (CAS 571-25-5)
- Rocuronium Impurity 34 (CAS CATO-C4X-124234)
- Testosterone Impurity 8 (Androstane-3,17-Dione) (Mixture of Diastereomers) (CAS 5982-99-0)
- Tofacitinib Impurity 100 (Enantiomer Mixture) (CAS CATO-C4X-1079100)
- Opicapone Impurity N3 (CAS 1402714-41-3)
- Ketoconazole Impurity 24 (CAS CATO-C4X-147224)
- 2-Fluoro-5-methylphenethyl oxazole-4-carboxylate (CAS 61151-98-2)
- (2Z)-2-[(3,4-Dimethoxyphenyl)methylidene]-3-phenyl-7-[3-(trifluoromethyl)phenoxy]-2,3-dihydro-1H-inden-1-one (CAS 337921-81-0)
- 7-Methoxy-3,3-dimethyl-2,3-dihydrobenzo[b]oxepine-5-carbaldehyde (CAS 280586-26-7)
- 5-Ethoxybenzo[d][1,3]dioxole (CAS 87590-41-8)
- Relebactam Impurity 11 (CAS CATO-C4X-214411)
- 4-Chloro-3-(3-chloro-5-fluorophenyl)propiophenone (CAS 898750-55-5)
- Neuropeptide K (human, porcine, rat) trifluoroacetate salt (CAS 96827-05-3)
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