1-(Tert-butoxycarbonyl)-4-(4-(trifluoromethyl)benzyl)piperidine-4-carboxylic acid CAS 1185036-68-3
| CAS No. | 1185036-68-3 |
| Molecular Formula | C19H24F3NO4 |
| Molecular Weight | 387.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(Tert-butoxycarbonyl)-4-(4-(trifluoromethyl)benzyl)piperidine-4-carboxylic acid.
1-(Tert-butoxycarbonyl)-4-(4-(trifluoromethyl)benzyl)piperidine-4-carboxylic acid (CAS 1185036-68-3) is a high-purity analytical reference standard with the molecular formula C19H24F3NO4 and a molecular weight of 387.39 g/mol.
1-(Tert-butoxycarbonyl)-4-(4-(trifluoromethyl)benzyl)piperidine-4-carboxylic acid (C19H24F3NO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H24F3NO4 |
| Molecular Weight | 387.39 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Tert Standards
- 1-(Tert-butoxycarbonyl)-4-(2-(trifluoromethyl)benzyl)piperidine-4-carboxylic acid (CAS 1185076-12-3)
- 1-(Tert-butoxycarbonyl)-4-(3-(trifluoromethyl)benzyl)piperidine-4-carboxylic acid (CAS 1187173-52-9)
- 2-{1-(tert-Butoxycarbonyl)-4-[4-(trifluoromethyl)phenyl]piperidin-4-yl}acetic acid (CAS 1439897-86-5)
- 1-(tert-Butoxycarbonyl)-3-(4-(trifluoromethyl)benzyl)piperidine-3-carboxylicacid (CAS 887344-24-3)
- 2-(1-(Tert-butoxycarbonyl)-4-(2-(trifluoromethyl)phenyl)piperidin-4-yl)acetic acid (CAS 2251054-33-6)
- 2-(1-(Tert-butoxycarbonyl)-4-(3-(trifluoromethyl)phenyl)piperidin-4-yl)acetic acid (CAS 644982-59-2)
- 2-(4-((tert-Butoxycarbonyl)amino)butoxy)ethyl 4-methylbenzenesulfonate (CAS 2681390-44-1)
- (1-(tert-butoxycarbonyl)-5-(4-methylpiperazine-1-carbonyl)-1H-indol-2-yl)boronic acid (CAS 913388-57-5)
Recommended Standards
- (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-((3-methoxybenzyl)amino)-9H-purin-9-yl)tetrahydrofuran-3,4-diol (CAS 101565-95-1)
- 4-[4-(methoxycarbonyl)-3-methyl-6-phenyl-1h-pyrazolo[3,4-b]pyridin-1-yl]benzoic acid (CAS 1011398-75-6)
- Tegoprazan Impurity 92 (CAS CATO-C4X-229792)
- N-(3-(Furan-2-yl)-1-(6-oxo-4-phenyl-1,6-dihydropyrimidin-2-yl)-1H-pyrazol-5-yl)cyclopropanecarboxamide (CAS 1207005-88-6)
- 1,5-Dimethyl-1H-indole-2-carboxylic acid (CAS 216210-59-2)
- 1-(3-Chloro-4-(4-iodo-1h-pyrazol-1-yl)phenyl)ethan-1-one (CAS 1342415-09-1)
- (2-Methoxy-5-methylphenyl)(5-methylthiophen-2-yl)methanol (CAS 944697-54-5)
- 5-Fluoro-2-(trifluoromethyl)benzal chloride (CAS 852462-70-5)
- 5-chloro-6-fluoro-1-tetrahydropyran-2-yl-indazole-4-carbonyl chloride (CAS 2736597-74-1)
- 2-((2-Chloro-5-(trifluoromethyl)phenyl)amino)-5-methoxybenzoic acid (CAS 883044-26-6)
- 2-(Bromomethyl)-6-cyano-3-(difluoromethyl)pyridine-5-acetic acid (CAS 1805507-73-6)
- Benzimidamide Hydrochloride Dihydrate (CAS 74222-83-6)
- 1-(3-(2-Bromophenyl)propyl)pyrrolidine (CAS 1704065-16-6)
- Delicious Peptide (bovine) (CAS 73984-05-1)
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