1-(tert-Butoxycarbonyl)-3-(4-(trifluoromethyl)benzyl)piperidine-3-carboxylicacid CAS 887344-24-3
| CAS No. | 887344-24-3 |
| Molecular Formula | C19H24F3NO4 |
| Molecular Weight | 387.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(tert-Butoxycarbonyl)-3-(4-(trifluoromethyl)benzyl)piperidine-3-carboxylicacid.
CATO supplies 1-(tert-Butoxycarbonyl)-3-(4-(trifluoromethyl)benzyl)piperidine-3-carboxylicacid (CAS 887344-24-3), a certified reference material (molecular formula C19H24F3NO4, MW 387.39 g/mol) for analytical method development and quality control.
1-(tert-Butoxycarbonyl)-3-(4-(trifluoromethyl)benzyl)piperidine-3-carboxylicacid (C19H24F3NO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H24F3NO4 |
| Molecular Weight | 387.39 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related tert Standards
- 1-(Tert-butoxycarbonyl)-4-(4-(trifluoromethyl)benzyl)piperidine-4-carboxylic acid (CAS 1185036-68-3)
- 1-(Tert-butoxycarbonyl)-4-(2-(trifluoromethyl)benzyl)piperidine-4-carboxylic acid (CAS 1185076-12-3)
- 1-(Tert-butoxycarbonyl)-4-(3-(trifluoromethyl)benzyl)piperidine-4-carboxylic acid (CAS 1187173-52-9)
- 2-{1-(tert-Butoxycarbonyl)-4-[4-(trifluoromethyl)phenyl]piperidin-4-yl}acetic acid (CAS 1439897-86-5)
- 2-(1-(Tert-butoxycarbonyl)-4-(2-(trifluoromethyl)phenyl)piperidin-4-yl)acetic acid (CAS 2251054-33-6)
- 2-(1-(Tert-butoxycarbonyl)-4-(3-(trifluoromethyl)phenyl)piperidin-4-yl)acetic acid (CAS 644982-59-2)
- 2-(4-((tert-Butoxycarbonyl)amino)butoxy)ethyl 4-methylbenzenesulfonate (CAS 2681390-44-1)
- (1-(tert-butoxycarbonyl)-5-(4-methylpiperazine-1-carbonyl)-1H-indol-2-yl)boronic acid (CAS 913388-57-5)
Recommended Standards
- (3R,4S,5S,6R)-2-((6-(Benzylamino)-7H-purin-7-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (CAS 56159-42-3)
- 1-(Tert-butyl) 4-methyl 4-(3-(trifluoromethyl)phenyl)piperidine-1,4-dicarboxylate (CAS 634466-24-3)
- (3R,4S,5S,6R)-2-((6-(Benzylamino)-3H-purin-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (CAS 56159-41-2)
- (2Z)-2-[(4-{[3-(trifluoromethyl)phenyl]methoxy}phenyl)methylidene]-1-azabicyclo[2.2.2]octan-3-one (CAS 865659-36-5)
- 5-Nitro-2-(2-(trifluoromethyl)phenyl)-2H-1,2,3-triazole-4-carboxylic acid (CAS 1708250-34-3)
- 3-Nitroso-2-phenylimidazo[1,2-a]pyridine (CAS 3672-37-5)
- 3-((Methylsulfonyl)methyl)-1H-pyrazole (CAS 1956365-20-0)
- 2-Fluoro-4-(trifluoromethyl)-6-((trimethylsilyl)ethynyl)aniline (CAS 1493799-73-7)
- [(4-Bromobutoxy)methyl]cyclopropane (CAS 712313-62-7)
- 2-Bromo-4-chloropyridin-3-amine (CAS 357263-45-7)
- 2-Methyl-4'-nitro-1,1'-biphenyl (CAS 33350-73-1)
- 4,5,6,7-Tetrahydro-3H-imidazo[4,5-c]pyridine-4-carboxylic acid (CAS 777819-31-5)
- 1,2,4,5-Tetrazine (CAS 290-96-0)
- DAPK Substrate Peptide (CAS 386769-53-5)
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