Quetiapine Impurity 51 CAS 1185170-04-0
| CAS No. | 1185170-04-0 |
| Molecular Formula | C21H25N3O4S |
| Molecular Weight | 415.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Quetiapine Impurity 51 (CAS 1185170-04-0, C21H25N3O4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Quetiapine Impurity 51 (C21H25N3O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Quetiapine Impurity 51 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H25N3O4S |
| Molecular Weight | 415.51 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Quetiapine Standards
- Quetiapine Impurity 35 (CAS 329216-65-1)
- Quetiapine impurity 73 (CAS CATO-C4X-124473)
- Quetiapine EP Impurity L (CAS 1371638-11-7)
- Quetiapine Impurity N2 (CAS 2206135-50-2)
- Quetiapine EP Impurity A (CAS 844639-07-2)
- Quetiapine Carboxylate Impurity (CAS 1011758-00-1)
- Quetiapine Impurity N3 (CAS 102893-57-2)
- Quetiapine Impurity 4 (CAS 1241800-24-7)
Recommended Standards
- sabeluzole (CAS 104383-17-7)
- Carbamazepine Impurity 6 (CAS 40421-03-2)
- Ethyl 4-([1,1'-biphenyl]-4-yl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate (CAS 1099644-42-4)
- Tert-butyl 4-(3-benzamidothiophene-2-carbonyl)piperazine-1-carboxylate (CAS 692738-33-3)
- Famotidine Impurity 61 (CAS CATO-C4X-139261)
- Axitinib Impurity 31 (CAS CATO-C4X-107131)
- Afoxolaner Impurity 33 (CAS CATO-C4X-313733)
- 1H-Pyrrole-2-sulfonyl fluoride (CAS 1909325-87-6)
- 4,6-diisopropylpyrimidin-5-amine (CAS 2168417-89-6)
- 2-((4,6-Dimethoxypyrimidin-2-yl)thio)benzoic acid (CAS 110284-79-2)
- 1-[(2,6-Difluorophenyl)methyl]-1,4-diazepane (CAS 1179515-18-4)
- (3S)-tert-butyl 3-((S)-2-(((benzyloxy)carbonyl)amino)propanamido)-4-hydroxy-5-(2,3,5,6-tetrafluorophenoxy)pentanoate (CAS 868565-58-6)
- 2-bromo-N-(2,4-dimethylphenyl)butanamide (CAS 244793-29-1)
- [3,5 Diiodo-Tyr7] Peptide T (CAS 128551-40-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com