Carbamazepine Impurity 6 CAS 40421-03-2
| CAS No. | 40421-03-2 |
| Molecular Formula | C15H10Br2ClNO |
| Molecular Weight | 415.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Carbamazepine Impurity 6.
As a process- or degradation-related impurity, Carbamazepine Impurity 6 (CAS 40421-03-2, C15H10Br2ClNO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Carbamazepine Impurity 6 (C15H10Br2ClNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Carbamazepine Impurity 6 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H10Br2ClNO |
| Molecular Weight | 415.51 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Carbamazepine Standards
- Carbamazepine Impurity 29 (CAS 2512216-68-9)
- Carbamazepine Impurity 39 (CAS 53003-61-5)
- Carbamazepine Impurity 28 (CAS 866873-98-5)
- Carbamazepine Impurity 23 (CAS CATO-C4X-118123)
- Carbamazepine Impurity 17 (CAS CATO-C4X-118117)
- Carbamazepine Impurity 11 (CAS 33948-20-8)
- Carbamazepine Impurity 12 (CAS 143667-53-2)
- Carbamazepine Impurity 22 (CAS CATO-C4X-118122)
Recommended Standards
- Tert-butyl 4-(3-benzamidothiophene-2-carbonyl)piperazine-1-carboxylate (CAS 692738-33-3)
- Quetiapine Impurity 35 (CAS 329216-65-1)
- N-Benzyl-5-methanesulfonyl-N,2-diphenylpyrimidin-4-amine (CAS 478080-89-6)
- Quetiapine Impurity 51 (CAS 1185170-04-0)
- Lumateperone Impurity 22 (CAS CATO-C4X-220122)
- Paliperidone Impurity 155 (CAS CATO-C4X-1724155)
- Policresulen Impurity 19 Sodium Salt (CAS 41481-17-8 (free acid))
- Methyl 3-(2-methylpyrimidin-4-yl)benzoate (CAS 579476-20-3)
- 2-Bromo-N-((3-methylpyridin-2-yl)methyl)benzamide (CAS 1333821-11-6)
- 2-(1H-Indol-3-yl)-N-methoxy-N-methylacetamide (CAS 132922-37-3)
- 2,4-Dichloro-1,5-dimethoxy-3-methylbenzene (CAS 153478-14-9)
- 5-Chloro-2-(pent-4-yn-1-yl)pyrimidine (CAS 126215-85-8)
- 2-Fluoro-N-methylacetamide (CAS 367-49-7)
- Acetyl Hexapeptide-39 (CAS 1382088-38-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com