Cimetidine Impurity 16 CAS 1185237-29-9
| CAS No. | 1185237-29-9 |
| Molecular Formula | - |
| Molecular Weight | 255.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Cimetidine Impurity 16 (CAS 1185237-29-9, C10H13D3N6S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Cimetidine Impurity 16 (C10H13D3N6S) is characterized by deuterium isotope labeling, a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Cimetidine Impurity 16 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H13D3N6S |
| Molecular Weight | 255.36 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 1 |
Related Cimetidine Standards
- Cimetidine EP Impurity B (CAS 138035-55-9)
- Cimetidine (CAS 51481-61-9)
- Cimetidine impurity 27 (CAS CATO-C4X-158927)
- Cimetidine Impurity 12 (CAS 75850-09-8)
- Cimetidine EP Impurity E (CAS 54237-72-8)
- Cimetidine EP Impurity A (CAS 52378-40-2)
- Cimetidine EP Impurity C (CAS 77076-18-7)
- Cimetidine EP Impurity D (CAS 70172-53-1)
Recommended Standards
- Tryptophan Impurity 20 (CAS CATO-C4X-137320)
- Pindolol-d7 (CAS 1185031-19-9)
- 5-Chloro-3-piperidin-4-yl-1H-indazole 956485-62-4 tert-butyl(1h-pyrrolo[2,3-b]pyridin-4-yl)methylcarbamate (CAS 956485-62-4)
- 3-Hydroxychrysene-d11 (CAS CATO-CCHM705019)
- Elagolix Impurity 35 (CAS CATO-C4X-206835)
- Cefpodoxime Impurity 49 (CAS CATO-C4X-157949)
- Tiotropium impurity 46 (CAS 7688-76-8)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (5-(dimethylamino)thiophen-2-yl)boronate (CAS 2223032-09-3)
- 2-(Cyclopropylamino)-2-methylpropanoic acid (CAS 1157990-33-4)
- Brexpiprazole Impurity 131 (CAS CATO-C4X-1131131)
- 1-((2,4-Difluorophenyl)sulfonyl)pyrrolidin-3-amine hydrochloride (CAS 1836563-03-1)
- N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-(pyridin-4-yl)quinoline-4-carboxamide (CAS 380212-69-1)
- 2-Fluoro-N-(2-phenoxyethyl)benzamide (CAS 329223-13-4)
- Des-Leu26-Tirzepatide (CAS CATO-CPTD788947)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com