Cimetidine EP Impurity C CAS 77076-18-7
| CAS No. | 77076-18-7 |
| Molecular Formula | C10H18N6OS |
| Molecular Weight | 270.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, Cimetidine EP Impurity C is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 270.35 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Cimetidine EP Impurity C (CAS 77076-18-7, C10H18N6OS) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Cimetidine EP Impurity C under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H18N6OS |
| Molecular Weight | 270.35 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 1 |
Related Cimetidine Standards
- Cimetidine EP Impurity A (CAS 52378-40-2)
- Cimetidine EP Impurity E (CAS 54237-72-8)
- Cimetidine Impurity 12 (CAS 75850-09-8)
- Cimetidine impurity 27 (CAS CATO-C4X-158927)
- Cimetidine Impurity 14 (CAS CATO-C4X-158914)
- Cimetidine Impurity 16 (CAS 1185237-29-9)
- Cimetidine EP Impurity B (CAS 138035-55-9)
- Cimetidine (CAS 51481-61-9)
Recommended Standards
- Tolbutamide (CAS 64-77-7)
- Raloxifene Impurity 7 (CAS 63675-74-1)
- (S)-2-(benzo[d]thiazol-2-ylamino)-2-phenylethan-1-ol (CAS CATO-C3D-263046)
- Articaine EP Impurity B (CAS 114176-52-2)
- Dapagliflozin Impurity 15 (CAS CATO-C4X-113815)
- Etapenem Impurity 42 (CAS CATO-C4X-163342)
- Miconazole EP Impurity I (CAS 24169-00-4)
- 2-({[(9h-fluoren-9-yl)methoxy]carbonyl}amino)-6-methylbenzoic acid (CAS 870150-57-5)
- (4-Chloro-2-fluoro-3-methylphenyl)boronic acid (CAS 944128-92-1)
- 4-(4-Fluorophenyl)-N-[4-(trifluoromethyl)phenyl]piperazine-1-carboxamide (CAS 1024120-50-0)
- 2-(2-bromopyridin-3-yloxy)-5-(chloromethyl)pyridine (CAS 1065484-75-4)
- 51861-34-8 Carbamic acid, dibutylthio-, S-benzyl ester (7CI) Carbamothioic acid, dibutyl-, S-(phenylmethyl) ester S-Benzyl dibutylthiocarbamate Benzyl N,N-dibutylthiolcarbamate CP 24591 S-(Phenylmethyl) dibutylcarbamothioate S-Benzyl dibutylthicarbamate (CAS 51861-34-8)
- Propofol Impurity 22 (CAS 1988-10-9)
- (Ser(PO?H?)3??·???)-Tau Peptide (379-408) trifluoroacetate salt (CAS 2022956-60-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com