2-({[(9h-fluoren-9-yl)methoxy]carbonyl}amino)-5-fluorobenzoic acid CAS 1185296-60-9

Purity 97%+In StockPharmaceutical Standards
CAS No.1185296-60-9
Molecular FormulaC22H16FNO4
Molecular Weight377.37 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-({[(9h-fluoren-9-yl)methoxy]carbonyl}amino)-5-fluorobenzoic acid CAS 1185296-60-9 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 377.37 g/mol gives 2-({[(9h-fluoren-9-yl)methoxy]carbonyl}amino)-5-fluorobenzoic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-({[(9h-fluoren-9-yl)methoxy]carbonyl}amino)-5-fluorobenzoic acid (CAS 1185296-60-9), molecular formula C22H16FNO4 and molecular weight 377.37 g/mol, is a CATO reference standard with documented purity and traceability.

2-({[(9h-fluoren-9-yl)methoxy]carbonyl}amino)-5-fluorobenzoic acid (C22H16FNO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC22H16FNO4
Molecular Weight377.37 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)15.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Halogen ContentF-containing
Nitrogen Atoms1

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