Methyl 3-cyclopropyl-1-(4-fluorophenyl)-6-(furan-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylate CAS 1011396-86-3
| CAS No. | 1011396-86-3 |
| Molecular Formula | C21H16FN3O3 |
| Molecular Weight | 377.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Methyl 3-cyclopropyl-1-(4-fluorophenyl)-6-(furan-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1011396-86-3), a certified reference material (molecular formula C21H16FN3O3, MW 377.37 g/mol) for analytical method development and quality control.
Methyl 3-cyclopropyl-1-(4-fluorophenyl)-6-(furan-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (C21H16FN3O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 3-cyclopropyl-1-(4-fluorophenyl)-6-(furan-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H16FN3O3 |
| Molecular Weight | 377.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Methyl Standards
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Recommended Standards
- Lasmiditan (CAS 439239-90-4)
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- 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-fluorobenzoic acid (CAS 1185296-64-3)
- tert-Butyl 3-carbamoylbenzyl(methyl)carbamate (CAS 1822671-40-8)
- 2-((3,5-Dioxo-2,3,4,5-tetrahydro-1,2,4-triazin-6-yl)amino)acetamide (CAS 307524-95-4)
- 1-[2-Methyl-6-(trifluoromethyl)pyrimidin-4-yl]piperidin-4-amine (CAS 944683-89-0)
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- 1-chloro-5-methoxy-2-methyl-4-nitrobenzene (CAS 100777-46-6)
- trans-2-(trifluoromethyl)cyclobutanamine;hydrochloride (CAS 2307778-24-9)
- Ethyl 5-(2-chlorophenoxy)-3-phenyl-1,2,4-triazine-6-carboxylate (CAS 338957-42-9)
- Lixisenatide (CAS 320367-13-3（free base）)
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