5-Fluoro-2-(2-piperidinyl)-1H-benzimidazole dihydrochloride CAS 1185399-19-2
| CAS No. | 1185399-19-2 |
| Molecular Formula | C12H14FN3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Fluoro-2-(2-piperidinyl)-1H-benzimidazole dihydrochloride is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-Fluoro-2-(2-piperidinyl)-1H-benzimidazole dihydrochloride (CAS 1185399-19-2), molecular formula C12H14FN3HCl and molecular weight 255.72 g/mol, is a CATO reference standard with documented purity and traceability.
5-Fluoro-2-(2-piperidinyl)-1H-benzimidazole dihydrochloride (C12H14FN3HCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Fluoro-2-(2-piperidinyl)-1H-benzimidazole dihydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H14FN3 2*HCl |
| Molecular Weight | 255.72 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Fluoro Standards
- 4-[(2-Fluoro-4-nitrophenoxy)methyl]-1-methylpiperidine (CAS 1000052-54-9)
- 3-Fluoro-4-((1-methylpiperidin-4-yl)methoxy)aniline (CAS 1000053-56-4)
- 2-Fluoro-5-iodo-4-methoxybenzoic acid (CAS 1000162-78-6)
- Ethyl 4-fluoro-3-ethoxybenzoate (CAS 1000207-63-5)
- 6-fluoro-4-iodo-1H-benzo[d]imidazole (CAS 1000308-33-7)
- 2-Fluoro-3-hydroxybenzonitrile (CAS 1000339-24-1)
- 1-(5-Fluoro-2-methylphenyl)pyrrolidine (CAS 1000339-32-1)
- 3-Fluoro-2-nitrobenzoic Acid (CAS 1000339-51-4)
Recommended Standards
- 3-Phenoxybenzothioamide (CAS 730971-69-4)
- (1R)-7-Chloro-6-fluoro-1-(2-isopropyl-4-methylpyridin-3-yl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione (CAS 2300966-23-6)
- (4-Cyclopentylpyrimidin-5-yl)boronic acid (CAS 1072945-80-2)
- Acid-PEG7-t-butyl ester (CAS 2134235-86-0)
- 2-Propenoic acid, 2-methyl-, polymer with ethenylbenzene and 2-hydroxypropyl 2-propenoate (CAS 70942-21-1)
- 3-Acetamido-5-amino-2,6-diiodobenzoic Acid (CAS 1713-08-2)
- 4,8-Dimethoxy-2-methylquinoline-6-carbaldehyde (CAS 89446-14-0)
- 4-Chloro-2-fluoromandelic Acid (CAS 1214345-56-8)
- (S)-2,2',3,3'-Tetrahydro-6,6'-bis(2,4,6-trimethylphenyl)-1,1'-spirobi[1H-indene]-7,7'-diol (CAS 1621066-75-8)
- CGMP Dependent Kinase Inhibitor Peptide (CAS 82801-73-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com