Ethyl 4-(Chlorosulfonyl)-5-methylthiophene-2-carboxylate CAS 1185853-40-0
| CAS No. | 1185853-40-0 |
| Molecular Formula | C8H9ClO4S2 |
| Molecular Weight | 268.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 4-(Chlorosulfonyl)-5-methylthiophene-2-carboxylate.
CATO supplies Ethyl 4-(Chlorosulfonyl)-5-methylthiophene-2-carboxylate (CAS 1185853-40-0), a certified reference material (molecular formula C8H9ClO4S2, MW 268.74 g/mol) for analytical method development and quality control.
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Ethyl 4-(Chlorosulfonyl)-5-methylthiophene-2-carboxylate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 268.74 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H9ClO4S2 |
| Molecular Weight | 268.74 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 2 |
Related Ethyl Standards
- 2-[4-(chlorosulfonyl)-2-fluorophenoxy]acetic acid (CAS 1016737-75-9)
- 3-(Chlorosulfonyl)-5-fluoro-4-methoxybenzoic acid (CAS 1099186-65-8)
- 5-(Chlorosulfonyl)-3-fluoro-2-methoxybenzoic acid (CAS 1375471-82-1)
- Ethyl 4-(chlorosulfonyl)-3-fluoro-1-methyl-1H-pyrrole-2-carboxylate (CAS 1638268-96-8)
- Ethyl 2-(chlorosulfonyl)-4-methylthiazole-5-carboxylate (CAS 89694-92-8)
- Ethyl 5-(chlorosulfonyl)-2-methylthiazole-4-carboxylate (CAS 93621-40-0)
- 3-(chlorosulfonyl)-4,5-dimethylbenzoyl chloride (CAS 1603443-25-9)
- Methyl 5-(chlorosulfonyl)-2,4-difluorobenzoate (CAS 1099632-51-5)
Recommended Standards
- 2-Chloro-1-[4-(2-hydroxyphenyl)piperazin-1-yl]propan-1-one (CAS 1178761-97-1)
- tert-Butyl 5-chloro-3,4-dihydro-2,6-naphthyridine-2(1H)-carboxylate (CAS 1196153-26-0)
- 3-[4-(3-Chloro-phenyl)-piperazin-1-yl]-propionic acid (CAS 117017-83-1)
- 6-Boc-4-chloro-5,6,7,8-tetrahydro-1,6-naphthyridine (CAS 1211495-11-2)
- Acebutolol Hydrochloride - Impurity H (Freebase) (CAS 1329613-31-1)
- Methyl 1,5-dimethyl-1H-pyrazole-3-carboxylate (CAS 10250-61-0)
- (2R,3R,4S,5R,6R)-2-(hydroxymethyl)-6-(3-nitrophenoxy)tetrahydro-2H-pyran-3,4,5-triol (CAS 52571-71-8)
- (S)-4-(Morpholin-2-yl)aniline (CAS 879206-06-1)
- 5-Chloro-6-fluoro pyridine-3-yl-acetonitrile (CAS 1227513-54-3)
- 2-(8-Fluoro-5-methylchroman-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1154741-05-5)
- 3-Amino-3-(2,4,5-trifluorophenyl)propanoic acid (CAS 682803-77-6)
- N-(4-Aminocyclohexyl)acrylamide hydrochloride (CAS 2446668-80-8)
- 3-(4-Acetyl-3,5-dimethyl-1H-pyrazol-1-yl)butanoic acid (CAS 890597-25-8)
- Semaglutide impurity 204 (CAS CATO-C4X-2226204)
Why CATO?
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