3-(Chlorosulfonyl)-5-fluoro-4-methoxybenzoic acid CAS 1099186-65-8
| CAS No. | 1099186-65-8 |
| Molecular Formula | C8H6ClFO5S |
| Molecular Weight | 268.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-(Chlorosulfonyl)-5-fluoro-4-methoxybenzoic acid (CAS 1099186-65-8) is a high-purity analytical reference standard with the molecular formula C8H6ClFO5S and a molecular weight of 268.65 g/mol.
Based on its molecular formula C8H6ClFO5S, 3-(Chlorosulfonyl)-5-fluoro-4-methoxybenzoic acid contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 268.65 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 3-(Chlorosulfonyl)-5-fluoro-4-methoxybenzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6ClFO5S |
| Molecular Weight | 268.65 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
Related Chlorosulfonyl Standards
- 2-[4-(chlorosulfonyl)-2-fluorophenoxy]acetic acid (CAS 1016737-75-9)
- 5-(Chlorosulfonyl)-3-fluoro-2-methoxybenzoic acid (CAS 1375471-82-1)
- Ethyl 4-(Chlorosulfonyl)-5-methylthiophene-2-carboxylate (CAS 1185853-40-0)
- Ethyl 4-(chlorosulfonyl)-3-fluoro-1-methyl-1H-pyrrole-2-carboxylate (CAS 1638268-96-8)
- Ethyl 2-(chlorosulfonyl)-4-methylthiazole-5-carboxylate (CAS 89694-92-8)
- Ethyl 5-(chlorosulfonyl)-2-methylthiazole-4-carboxylate (CAS 93621-40-0)
- 3-(chlorosulfonyl)-4,5-dimethylbenzoyl chloride (CAS 1603443-25-9)
- Methyl 5-(chlorosulfonyl)-1-isopropyl-1h-pyrazole-3-carboxylate (CAS 1260658-86-3)
Recommended Standards
- 1-(4-Chloro-3-nitrobenzyl)pyrrolidine-2,5-dione (CAS 1097788-45-8)
- 3-(5-(Chloromethyl)-1,2,4-oxadiazol-3-yl)-4-methoxybenzoic acid (CAS 1119450-89-3)
- 3-Chloro-6,7-dimethoxyquinoxaline-2-carboxylic acid (CAS 122234-54-2)
- Riluzole Impurity 27 (CAS 2273706-77-5)
- (1-((1-Methyl-1h-indazol-3-yl)methyl)cyclopropyl)methanamine (CAS 1495991-71-3)
- Ethyl 1-([1,1'-biphenyl]-4-yl)cyclopropanecarboxylate (CAS 1380650-55-4)
- rac-Glycerol 1-phosphate Sodium Salt Hydrate (CAS 17603-42-8)
- 3-(Dihydroxyboranyl)-2,5-difluorobenzoic acid (CAS 2377605-94-0)
- Methyl 6-methylthieno[2,3-b]quinoline-2-carboxylate (CAS 918145-25-2)
- 4-(Chloromethyl)-2-methyloxazole (CAS 141399-53-3)
- 6-Amino-2-phenylquinoline-4-carboxylic Acid (CAS 109540-22-9)
- 2-(tert-Butoxycarbonyl)hexahydropyrrolo[3,4-c]pyrrole-3a(1H)-carboxylic acid (CAS 1823396-97-9)
- (4-Cyclopentylphenyl)boronic acid (CAS 945837-57-0)
- Erythropoietin Mimetic Peptide Sequence 20 (CAS 203397-62-0)
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