4-Chloro-2-fluoro-1-(2,2,2-trifluoroethyl)benzene CAS 1186194-79-5
| CAS No. | 1186194-79-5 |
| Molecular Formula | C8H5ClF4 |
| Molecular Weight | 212.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 4-Chloro-2-fluoro-1-(2,2,2-trifluoroethyl)benzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
4-Chloro-2-fluoro-1-(2,2,2-trifluoroethyl)benzene (CAS 1186194-79-5) is a high-purity analytical reference standard with the molecular formula C8H5ClF4 and a molecular weight of 212.57 g/mol.
The molecular framework of 4-Chloro-2-fluoro-1-(2,2,2-trifluoroethyl)benzene (C8H5ClF4) is characterized by fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H5ClF4 |
| Molecular Weight | 212.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 2-Chloro-1-fluoro-4-(2,2,2-trifluoroethyl)-benzene (CAS 1099597-22-4)
- 1-Chloro-3-fluoro-2-(2,2,2-trifluoroethyl)benzene (CAS 1099597-29-1)
- 1-Chloro-3-fluoro-4-methyl-2-(trifluoromethyl)benzene (CAS 1099597-48-4)
- 2-Chloro-6-fluoro-3-methylbenzotrifluoridehydrochloride (CAS 1099597-61-1)
- 1-Chloro-2-fluoro-3-(2,2,2-trifluoroethyl)benzene (CAS 1099598-23-8)
- 4-Chloro-1-fluoro-2-(2,2,2-trifluoroethyl)benzene (CAS 1099598-24-9)
- 1-Chloro-3-(1,1-difluoroethyl)-2,4-difluorobenzene (CAS 1138444-87-7)
- 1-Chloro-2-(1,1-difluoroethyl)-4,5-difluorobenzene (CAS 1138444-88-8)
Recommended Standards
- 1-Chloro-4-(1,1-difluoroethyl)-2,5-difluorobenzene (CAS 1138444-89-9)
- 1-Chloro-2-fluoro-4-(2,2,2-trifluoroethyl)benzene (CAS 1186194-82-0)
- 1-(2-Chloro-1,1-difluoroethyl)-2,4-difluorobenzene (CAS 1204296-01-4)
- 1-Chloro-2-fluoro-3-methyl-4-(trifluoromethyl)benzene (CAS 1805112-84-8)
- 2-Ethylbenzene-1-sulfonamide (CAS 85-92-7)
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- Semaglutide impurity 258 (CAS CATO-C4X-2226258)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com