1-(2-Chloro-1,1-difluoroethyl)-2,4-difluorobenzene CAS 1204296-01-4
| CAS No. | 1204296-01-4 |
| Molecular Formula | C8H5ClF4 |
| Molecular Weight | 212.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 1-(2-Chloro-1,1-difluoroethyl)-2,4-difluorobenzene (CAS 1204296-01-4), a certified reference material (molecular formula C8H5ClF4, MW 212.57 g/mol) for analytical method development and quality control.
The molecular framework of 1-(2-Chloro-1,1-difluoroethyl)-2,4-difluorobenzene (C8H5ClF4) is characterized by fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(2-Chloro-1,1-difluoroethyl)-2,4-difluorobenzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5ClF4 |
| Molecular Weight | 212.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 2-Chloro-1-fluoro-4-(2,2,2-trifluoroethyl)-benzene (CAS 1099597-22-4)
- 1-Chloro-3-fluoro-2-(2,2,2-trifluoroethyl)benzene (CAS 1099597-29-1)
- 1-Chloro-3-fluoro-4-methyl-2-(trifluoromethyl)benzene (CAS 1099597-48-4)
- 2-Chloro-6-fluoro-3-methylbenzotrifluoridehydrochloride (CAS 1099597-61-1)
- 1-Chloro-2-fluoro-3-(2,2,2-trifluoroethyl)benzene (CAS 1099598-23-8)
- 4-Chloro-1-fluoro-2-(2,2,2-trifluoroethyl)benzene (CAS 1099598-24-9)
- 1-Chloro-3-(1,1-difluoroethyl)-2,4-difluorobenzene (CAS 1138444-87-7)
- 1-Chloro-2-(1,1-difluoroethyl)-4,5-difluorobenzene (CAS 1138444-88-8)
Recommended Standards
- 1-Chloro-2-fluoro-4-(2,2,2-trifluoroethyl)benzene (CAS 1186194-82-0)
- 1-Chloro-2-fluoro-3-methyl-4-(trifluoromethyl)benzene (CAS 1805112-84-8)
- 4-Chloro-2-fluoro-1-(2,2,2-trifluoroethyl)benzene (CAS 1186194-79-5)
- 1-(Chloromethyl)-2,3,5,6-tetrafluoro-4-methylbenzene (CAS 60903-84-6)
- 2-(4-(Bromomethyl)phenyl)-2-oxoacetic acid (CAS 102047-01-8)
- 3-(4-Bromophenyl)-7-propyl-4,6,7,8-tetrahydrocinnolin-5(1H)-one (CAS 1023531-55-6)
- 1-Cyclohexyl-5-oxo-N-(4-phenoxyphenyl)pyrrolidine-3-carboxamide (CAS 669696-41-7)
- 2,3-Dimethyl-3H-imidazo[4,5-b]pyridin-7-amine (CAS 1512124-64-9)
- (1S,3R,6S)-4-oxo-5-azaspiro[2.4]Heptane-1,6-dicarboxylic acid (CAS 1868986-50-8)
- (R)-2-((Benzyloxy)methyl)pyrrolidine (CAS 911313-89-8)
- 3,5-Dichloro-2(1H)-pyrazinone (CAS 130879-62-8)
- Methyl pyrazolo[1,5-b]pyridazine-3-carboxylate (CAS 53946-83-1)
- 5,6-Dimethyl-2-(2-(methylthio)ethyl)pyrimidin-4(1H)-one (CAS 88570-30-3)
- 263251-78-1 NMG938VJ6T D-3 Tavilermide [USAN:INN] UNII-NMG938VJ6T MIM-D3 MIM-D 3 D 3 (peptide) Tavilermide (CAS 263251-78-1)
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