Ethyl 4-methoxy-2-(trifluoromethoxy)benzoate CAS 1186195-26-5
| CAS No. | 1186195-26-5 |
| Molecular Formula | C11H11F3O4 |
| Molecular Weight | 264.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 4-methoxy-2-(trifluoromethoxy)benzoate.
Ethyl 4-methoxy-2-(trifluoromethoxy)benzoate (CAS 1186195-26-5) is a high-purity analytical reference standard with the molecular formula C11H11F3O4 and a molecular weight of 264.20 g/mol.
The molecular framework of Ethyl 4-methoxy-2-(trifluoromethoxy)benzoate (C11H11F3O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Ethyl 4-methoxy-2-(trifluoromethoxy)benzoate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H11F3O4 |
| Molecular Weight | 264.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
Related Ethyl Standards
- 3-(2-Methoxy-5-(trifluoromethoxy)phenyl)propanoic acid (CAS 1017779-17-7)
- 4-Methoxy-3-[(2,2,2-trifluoroethoxy)methyl]-benzoic acid (CAS 1119449-79-4)
- Ethyl 3-methoxy-4-(trifluoromethoxy)benzoate (CAS 1261582-69-7)
- 3-(4-Methoxy-3-(trifluoromethoxy)phenyl)propanoic acid (CAS 1261587-75-0)
- (2-Methoxy-5-(pentafluoro-lambda6-sulfanyl)phenyl)methanol (CAS 1240257-12-8)
- Ethyl 5-methoxy-7-nitro-1H-indole-2-carboxylate (CAS 13838-44-3)
- Ethyl 7-methoxy-5-nitro-1H-indole-2-carboxylate (CAS 176956-21-1)
- Methyl 2-(2-methoxy-4-(1H-tetrazol-1-yl)phenoxy)acetate (CAS 936081-95-7)
Recommended Standards
- N-(2-Methoxyethyl)-4-nitro-2-(trifluoromethyl)aniline (CAS 1183236-47-6)
- 2-(Pyridin-4-yl)-5-(trifluoromethyl)benzo[d]oxazole (CAS 1192018-99-7)
- 3-((4-Nitro-2-(trifluoromethyl)phenyl)amino)propan-1-ol (CAS 115416-49-4)
- 2-(Pyridin-4-yl)-6-(trifluoromethyl)benzo[d]oxazole (CAS 1192019-02-5)
- (R)-3-(2,2,2-Trifluoro-ethyl)-piperazine-1-carboxylic acid tert-butyl ester (CAS 1240582-23-3)
- 3-Amino-1H-pyrrolo[2,3-b]pyridine-4-carboxylic acid (CAS 1190321-98-2)
- 2-((2-Morpholinoquinolin-8-yl)oxy)-N-(m-tolyl)acetamide (CAS 941989-23-7)
- 1-(2,4,6-Trichlorophenyl)-3-(5-[a-(3-tert-butyl-4-hydroxyphenoxy)-N-tetradecanamido]-2-chloroanilino)-4-[3,4-dimethyloxyphenyl]azo-5-pyrazolone (CAS 65293-90-5)
- N-Methyl-1-(3-methylpyridin-2-yl)propan-2-amine (CAS 937638-36-3)
- (2S,4S)-4-Benzylpyrrolidine-2-carboxylicacidhydrochloride (CAS 83623-77-2)
- ((3,5-Dimethoxyphenyl)ethynyl)trimethylsilane (CAS 400608-30-2)
- 2-(Pyridin-2-yl)phthalazin-1(2H)-one (CAS 307324-42-1)
- Prednisolone 21-Acetate 17-Valerate (CAS 72064-79-0)
- Allo-D-Ile17-Tirzepatide (CAS CATO-CPTD788962)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com