N-(3-((3-(((tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-1-yl)methyl)-2-chloropyridin-4-yl)pivalamide CAS 1186310-83-7
| CAS No. | 1186310-83-7 |
| Molecular Formula | C22H38ClN3O2Si |
| Molecular Weight | 440.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(3-((3-(((tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-1-yl)methyl)-2-chloropyridin-4-yl)pivalamide.
CATO supplies N-(3-((3-(((tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-1-yl)methyl)-2-chloropyridin-4-yl)pivalamide (CAS 1186310-83-7), a certified reference material (molecular formula C22H38ClN3O2Si, MW 440.09 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, N-(3-((3-(((tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-1-yl)methyl)-2-chloropyridin-4-yl)pivalamide is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 440.09 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(3-((3-(((tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-1-yl)methyl)-2-chloropyridin-4-yl)pivalamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H38ClN3O2Si |
| Molecular Weight | 440.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Recommended Standards
- Benzbromarone Impurity 4 (CAS 152831-00-0)
- N-(6-((3-((tert-Butyldimethylsilyloxy)methyl)pyrrolidin-1-yl)methyl)-2-chloropyridin-3-yl)pivalamide (CAS 1203499-53-9)
- 1`-hydroxybenzbromarone (CAS 125729-46-6)
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