Dabigatran Impurity 8 Hydrochloride CAS 1187067-68-0
| CAS No. | 1187067-68-0 |
| Molecular Formula | C18H20N4O5 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 408.84 g/mol gives Dabigatran Impurity 8 Hydrochloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Dabigatran Impurity 8 Hydrochloride (CAS 1187067-68-0), molecular formula C18H20N4O5HCl and molecular weight 408.84 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C18H20N4O5HCl, Dabigatran Impurity 8 Hydrochloride contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 408.84 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H20N4O5 HCl |
| Molecular Weight | 408.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Dabigatran Standards
- Dabigatran Impurity 136 (CAS 1015167-27-7)
- Dabigatran Acyl-β-D-Glucuronide (CAS 1015167-40-4)
- Dabigatran Acyl-B-D-Glucuronide-d3 as TFA Salt (CAS 1015167-40-4 (unlabeled))
- Dabigatran Acyl-β-D-Glucuronide-D3 TFA Salt (CAS 1015167-40-4 (unlabelled))
- Dabigatran Acyl-β-D-Glucuronide TFA Salt (CAS 1015167-40-4 （free base）)
- Dabigatran Impurity 68 (CAS 103041-38-9)
- Dabigatran Impurity 3 Hydrobromide (CAS 1046806-03-4)
- Dabigatran Impurity 85 (CAS 104961-64-0)
Recommended Standards
- 1-(4-(2-Aminoethyl)-3-methylpiperazin-1-yl)ethanone (CAS 1353956-52-1)
- 0156AD 1185139-29-0 3-Tetrazol-1-yl-1H-pyrazole-4-carboxylic aciddihydrochloride C5H6Cl2N6O2 (CAS 1185139-29-0)
- 5-(Tert-butyl)-3-hydroxyindolin-2-one (CAS 1249966-00-4)
- 1-(Bromomethyl)naphthalene-2-carboxylic acid (CAS 87262-95-1)
- 3-Amino-6-piperidin-1-ylpyridine-2-carbonitrile (CAS 1215852-53-1)
- 4-[2-(Anilinocarbonyl)hydrazino]-4-oxobutanoic acid (CAS 327066-08-0)
- 2-(3-Fluoropyridin-4-yl)acetic acid (CAS 1000545-36-7)
- tert-Butyl N-(1-Cyano-2-methylcyclohexyl)carbamate (CAS 1392491-69-8)
- 1-Phenyl-N-[3-(trifluoromethyl)phenyl]cyclopentane-1-carboxamide (CAS 512795-92-5)
- 30003-72-6 insulin chain b oxidized (CAS 30003-72-6)
Why CATO?
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