Dabigatran Impurity 85 CAS 104961-64-0
| CAS No. | 104961-64-0 |
| Molecular Formula | C8H10N2O2 |
| Molecular Weight | 166.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Dabigatran Impurity 85 (C8H10N2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Dabigatran Impurity 85 (CAS 104961-64-0), a pharmacopoeial impurity reference standard (molecular formula C8H10N2O2, MW 166.18 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H10N2O2 |
| Molecular Weight | 166.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 2 |
Related Dabigatran Standards
- Dabigatran Impurity 86 (CAS 18358-63-9)
- Dabigatran Impurity 34 (CAS 58906-62-0)
- Dabigatran Impurity 35 (CAS 265659-62-9)
- Dabigatran Impurity 36 (CAS 265659-61-8)
- Dabigatran Impurity 94 (CAS 58906-64-2)
- Dabigatran Impurity 42 (CAS 42288-26-6)
- Dabigatran Impurity 96 (CAS 16156-50-6)
- Dabigatran Etexilate Impurity 84 (CAS 175867-55-7)
Recommended Standards
- Tofacitinib Impurity 52 (CAS 694495-63-1)
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- Lenvatinib Impurity 97 (CAS 75955-30-5)
- Uridine Impurity 14 (CAS 872710-80-0)
- Olmesartan Impurity 79 (CAS 172875-59-1)
- Methotrexate Impurity 63 (CAS 2801801-56-7)
- 3-Methyl-4-((tetrahydro-2H-pyran-2-yl)methoxy)aniline (CAS 940009-03-0)
- Ethyl N-Cbz-morpholine-2-carboxylate (CAS 1226776-83-5)
- 87206-01-7 N-Hexadecanoyl-L-homoserine lactone MFCD18382092 C16-HSL / N-Palmitoyl-L-homoserine (CAS 87206-01-7)
- (3R)-3-Hydroxy-1-(4-nitrobenzyloxycarbonyl)pyrrolidine (CAS 105601-88-5)
- Benzyl 7-fluoro-2-methyl-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylate (CAS 1797376-37-4)
- 2,4,6-Trichlorobenzothioamide (CAS 91979-32-7)
- Semaglutide Impurity 131 (CAS 2618647-80-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com