Baricitinib Impurity 20 CAS 1187595-85-2
| CAS No. | 1187595-85-2 |
| Molecular Formula | C7H10N2O2S |
| Molecular Weight | 186.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Baricitinib Impurity 20 (CAS 1187595-85-2), a pharmacopoeial impurity reference standard (molecular formula C7H10N2O2S, MW 186.23 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Baricitinib Impurity 20 (C7H10N2O2S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 186.23 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H10N2O2S |
| Molecular Weight | 186.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Baricitinib Standards
- Baricitinib Impurity 10 (CAS 952518-97-7)
- Baricitinib Impurity 13 (CAS 2227194-01-4)
- Baricitinib Impurity 79 (CAS CATO-C4X-226079)
- Baricitinib Impurity 32 (CAS 269410-08-4)
- Baricitinib Impurity 18 (CAS 1153949-11-1)
- Baricitinib Impurity 96 (CAS CATO-C4X-226096)
- Baricitinib Impurity 135 (CAS 2101302-36-5)
- Baricitinib Impurity 62 (CAS 2101302-47-8)
Recommended Standards
- Pazopanib Impurity 25 (CAS 6274-28-8)
- SAR107375E Impurity 7 (CAS 5877-96-3)
- Pazopanib Impurity 19 (CAS 6973-09-7)
- Methyl 3-methylbenzenesulfonate (CAS 126865-07-4)
- Ceftezole Impurity 5 (CAS CATO-C4X-23095)
- Rebamipide Impurity 65 (CAS CATO-C4X-152365)
- Felodipine Impurity 12 (CAS 74073-22-6)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com