Baricitinib Impurity 32 CAS 269410-08-4
| CAS No. | 269410-08-4 |
| Molecular Formula | C9H15BN2O2 |
| Molecular Weight | 194.04 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Baricitinib Impurity 32 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Baricitinib Impurity 32 (CAS 269410-08-4) is a certified pharmaceutical impurity reference standard with the molecular formula C9H15BN2O2 and a molecular weight of 194.04 g/mol.
Structurally, Baricitinib Impurity 32 (C9H15BN2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 3.5, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 194.04 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C9H15BN2O2 |
| Molecular Weight | 194.04 g/mol |
| Appearance | White to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
Related Baricitinib Standards
- Baricitinib Impurity 18 (CAS 1153949-11-1)
- Baricitinib Impurity 135 (CAS 2101302-36-5)
- Baricitinib Impurity 62 (CAS 2101302-47-8)
- Baricitinib Impurity 97 (CAS CATO-C4X-226097)
- Baricitinib Impurity 20 (CAS 1187595-85-2)
- Baricitinib Impurity 10 (CAS 952518-97-7)
- Baricitinib Impurity 13 (CAS 2227194-01-4)
- Baricitinib Impurity 86 (CAS CATO-C4X-226086)
Recommended Standards
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