6-chloro-2-fluoro-3-iodo-pyridine CAS 1187732-65-5
| CAS No. | 1187732-65-5 |
| Molecular Formula | C5H2ClFIN |
| Molecular Weight | 257.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-chloro-2-fluoro-3-iodo-pyridine (C5H2ClFIN) contains a nitrile group, fluorine/chlorine/iodine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
6-chloro-2-fluoro-3-iodo-pyridine (CAS 1187732-65-5), molecular formula C5H2ClFIN and molecular weight 257.43 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-chloro-2-fluoro-3-iodo-pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H2ClFIN |
| Molecular Weight | 257.43 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl/I-containing |
| Nitrogen Atoms | 1 |
Related chloro Standards
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- 4-Chloro-5-fluoro-2-iodopyridine (CAS 1211529-70-2)
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- 4-Chloro-2-fluoro-3-iodopyridine (CAS 1211590-40-7)
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