Semaglutide Impurity 130 CAS 1188328-40-6
| CAS No. | 1188328-40-6 |
| Molecular Formula | C40H72N2O10 |
| Molecular Weight | 741.01 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Semaglutide Impurity 130 (CAS 1188328-40-6) is a certified pharmaceutical impurity reference standard with the molecular formula C40H72N2O10 and a molecular weight of 741.01 g/mol.
Based on its molecular formula C40H72N2O10, Semaglutide Impurity 130 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 741.01 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C40H72N2O10 |
| Molecular Weight | 741.01 g/mol |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 2 |
Related Semaglutide Standards
- Semaglutide impurity 39 (CAS CATO-C4X-222639)
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- Semaglutide impurity 290 (CAS CATO-C4X-2226290)
- Semaglutide Impurity 146 (CAS 2645421-68-5)
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Recommended Standards
- Sulfo-Cy5 amine (CAS 2183440-44-8)
- Tri([1,1'-biphenyl]-2-yl)(octadecyl)silane (CAS 18822-32-7)
- L-arabino-D-allo-Tridec-12-enose, 3,7:6,10-dianhydro-2,4,5,12,13-pentadeoxy-8,9,11-tris-O-[(1,1-dimethylethyl)dimethylsilyl]-13-iodo- (CAS 252905-91-2)
- 2-Debenzoyl-7,10-bis[O-(triethylsilyl)]-10-deacetyl-13-O-trimethylsilyl Baccatin III (CAS 159383-94-5)
- Ethambutol Impurity 10 (CAS 78213-39-5)
- Leuprorelin EP Impurity K Acetate (CAS CATO-C4X-182212)
- Deoxycholic acid Impurity 10 (CAS 881023-82-1)
- [4-(6-Methylquinolin-2-yl)phenyl]amine (CAS 1224953-47-2)
- 2',3'-Dihydro-4'H-spiro[cyclopentane-1,1'-naphthalen]-4'-one (CAS 4889-95-6)
- 2-(3,4-Difluorophenoxy)-5-methylaniline (CAS 946773-98-4)
- 2-Acetyl-2,3-dihydroisoquinolin-4(1H)-one (CAS 105121-99-1)
- 1-(Dimethylamino)-1H-indole-2,3-dione (CAS 124315-67-9)
- 2-chloro-7-(trifluoromethyl)-3,4-dihydroquinazolin-4-one (CAS 159870-93-6)
- Pancreatic Polypeptide (human) trifluoroacetate salt (CAS 75976-10-2)
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