((2-Fluoro-5-(trifluoromethyl)phenyl)ethynyl)trimethylsilane CAS 1188446-61-8
| CAS No. | 1188446-61-8 |
| Molecular Formula | C12H12F4Si |
| Molecular Weight | 260.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to fluorine substitution, an aromatic ring system, ((2-Fluoro-5-(trifluoromethyl)phenyl)ethynyl)trimethylsilane is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 260.30 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
((2-Fluoro-5-(trifluoromethyl)phenyl)ethynyl)trimethylsilane (CAS 1188446-61-8), molecular formula C12H12F4Si and molecular weight 260.30 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), ((2-Fluoro-5-(trifluoromethyl)phenyl)ethynyl)trimethylsilane meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H12F4Si |
| Molecular Weight | 260.30 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
Related Fluoro Standards
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- 2-Fluoro-5-(morpholine-4-sulfonyl)aniline (CAS 1017390-45-2)
- 1-{3-fluoro-4-[methyl(pyridin-2-ylmethyl)amino]phenyl}ethan-1-ol (CAS 1153369-70-0)
- 4-fluoro-1-N-[2-(3-methylphenoxy)ethyl]benzene-1,2-diamine (CAS 1270795-86-2)
- 1-(3-Fluoro-4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol (CAS 1416345-11-3)
- 1-(4-Fluoro-2-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol (CAS 1416348-27-0)
- 2-Fluoro-N-((6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)methyl)aniline (CAS 877812-00-5)
Recommended Standards
- 3-N-methyl-4-(3-phenyl-1,2,4-oxadiazol-5-yl)-1H-pyrazole-3,5-diamine (CAS 1188304-97-3)
- (R)-1-(2-(Benzyloxy)-5-fluorophenyl)propan-2-ol (CAS 1238894-66-0)
- Tolmetin-d3 (CAS 1184998-16-0)
- N1-isopropyl-N1-(3-(trifluoromethyl)benzyl)ethane-1,2-diamine (CAS 1306559-16-9)
- 3-(3-methyldiazirin-3-yl)propan-1-ol (CAS 16297-94-2)
- n-Cyclopentyl-3-isopropyl-1,2,4-oxadiazol-5-amine (CAS 1259064-32-8)
- 7,7-Difluoro-4-azaspiro[2.5]Octane hydrochloride (CAS 2229309-97-9)
- 3-Methyl-5-(4-(trifluoromethyl)phenyl)isoxazole-4-carbaldehyde (CAS 1208081-38-2)
- 2-(iodomethyl)bicyclo[2.2.1]heptane (CAS 858018-16-3)
- 2-phenyl-1,2,5-thiadiazolidine 1,1-dioxide (CAS 503310-73-4)
- 2,2-Dimethyl-2H,3H,5H,9bH-[1,3]thiazolo[2,3-a]isoindol-5-one (CAS 3063-82-9)
- Linagliptin Impurity 32 (CAS 109113-72-6)
- Tert-butyl (1-(2-fluorophenyl)cyclopropyl)carbamate (CAS 1338218-86-2)
- Semaglutide Impurity 3 (CAS CATO-C4X-22263)
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