1-[6-Bromo-3-pyridyl]-2,2,2-trifluoroethanol CAS 1188477-81-7
| CAS No. | 1188477-81-7 |
| Molecular Formula | C7H5BrF3NO |
| Molecular Weight | 256.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1-[6-Bromo-3-pyridyl]-2,2,2-trifluoroethanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
1-[6-Bromo-3-pyridyl]-2,2,2-trifluoroethanol (CAS 1188477-81-7), molecular formula C7H5BrF3NO and molecular weight 256.02 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system, 1-[6-Bromo-3-pyridyl]-2,2,2-trifluoroethanol is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 256.02 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C7H5BrF3NO |
| Molecular Weight | 256.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 3-Bromo-alpha-(trifluoromethyl)pyridine-4-methanol (CAS 1092459-54-5)
- 3-Bromo-2-(difluoromethoxy)-5-fluoroaniline (CAS 1096884-90-0)
- 5-Bromo-1-(2,2,2-trifluoro-ethyl)-1H-pyridin-2-one (CAS 1114563-10-8)
- 4-Bromo-3-(trifluoromethoxy)aniline (CAS 116369-25-6)
- 5-Bromo-alpha-(trifluoromethyl)pyridine-3-methanol (CAS 1204234-60-5)
- (5-Bromo-3-(trifluoromethyl)pyridin-2-yl)methanol (CAS 1206968-90-2)
- 3-Bromo-2-methoxy-4-(trifluoromethyl)pyridine (CAS 1211521-34-4)
- 4-Bromo-3-methoxy-2-(trifluoromethyl)pyridine (CAS 1211526-81-6)
Recommended Standards
- 1-(6-Bromopyridin-2-yl)-2,2,2-trifluoroethan-1-ol (CAS 1093880-21-7)
- 2-Bromo-6-methoxy-4-(trifluoromethyl)pyridine (CAS 1211536-10-5)
- 1-(2-Bromopyridin-3-yl)-2,2,2-trifluoroethan-1-ol (CAS 1092459-51-2)
- 4-Bromo-2-methoxy-5-(trifluoromethyl)pyridine (CAS 1211580-59-4)
- N4-(2-Bromophenyl)-N2-hexyl-L-asparagine (CAS 1048001-59-7)
- Methanesulfonamide (CAS 3144-09-0)
- 2-(5-(4-Methoxyphenyl)-1,3,4-oxadiazol-2-yl)benzoic acid (CAS 56894-46-3)
- 2-Methoxy-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid 1-[[(cyclohexyloxy) carbonyl]oxy]ethyl ester (Candesartan Cilexetil Impurit) (CAS 1246818-56-3)
- Peridine Impurity 20 (CAS 852627-75-9)
- Argatroban Impurity 40 (CAS CATO-C4X-100740)
- 3-[(chlorosulfonyl)(methyl)amino]-2-methylpropanenitrile (CAS 1250149-70-2)
- 1-Acetyl-4-(tert-butoxycarbonyl)piperazine-2-carboxylic acid (CAS 1361111-78-5)
- ((1S,3S)-3-Aminocyclohexyl)methanol (CAS 1202411-97-9)
- Semaglutide impurity 72 (CAS CATO-C4X-222672)
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