Semaglutide impurity 72 CAS CATO-C4X-222672
| CAS No. | CATO-C4X-222672 |
| Molecular Formula | C43H79N3O13 |
| Molecular Weight | 846.10 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Semaglutide impurity 72 (CAS CATO-C4X-222672) is a certified pharmaceutical impurity reference standard with the molecular formula C43H79N3O13 and a molecular weight of 846.10 g/mol.
The molecular framework of Semaglutide impurity 72 (C43H79N3O13) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C43H79N3O13 |
| Molecular Weight | 846.10 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
Related Semaglutide Standards
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Recommended Standards
- 2,3-Bis((3,7,11,15-tetramethylhexadecanoyl)oxy)propyl (2-(trimethylammonio)ethyl) phosphate (CAS 64626-70-6)
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- 61596-53-0 HE0P2D9ZLS 1,2-Diarachidoyl-sn-glycero-3-phosphocholine UNII-HE0P2D9ZLS 3,5,9-Trioxa-4-phosphanonacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-((1-oxoeicosyl)oxy)-, inner salt, 4-oxide, (7R)- l-alpha-Diarachidinoyl lecithin (CAS 61596-53-0)
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