Nicotine impurity-d3 CAS 1189805-47-7
| CAS No. | 1189805-47-7 |
| Molecular Formula | - |
| Molecular Weight | 181.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Nicotine impurity-d3 (CAS 1189805-47-7), a pharmacopoeial impurity reference standard (molecular formula C10H11D3N2O, MW 181.25 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to deuterium isotope labeling, a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Nicotine impurity-d3 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 181.25 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Nicotine impurity-d3 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H11D3N2O |
| Molecular Weight | 181.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 2 |
Related Nicotine Standards
- Nicotine EP Impurity E (Mixture of Diastereomers) (CAS 491-26-9)
- Nicotine Impurity 2 (CAS 2820-55-5)
- rac-Nicotine EP Impurity E (CAS 63551-14-4)
- Nicotine impurity 17 (CAS 101540-79-8)
- S-Nicotine-5-carboxaldehyde (CAS 852238-97-2)
- Nicotine Impurity 14 (CAS 125630-26-4)
- Nicotine Impurity 1 (CAS 887355-56-8)
- Nicotine impurity 16 (CAS CATO-C4X-201916)
Recommended Standards
- 2-PETA 2-Pyridylethyl Thiolacetate 59020-97-2 Ethanethioic acid S-[2-(2-Pyridinyl)ethyl] Ester (CAS 59020-97-2)
- (1'S,2'S)-Nicotine-1'-Oxide-d3 (CAS CATO-CCHM705659)
- rac-trans-Nicotine-1�-oxide D3 (CAS 29419-55-4)
- 2-Methylbenzo[d]thiazole-6,7-diamine (CAS 101258-10-0)
- Lipoic acid impurity N1 (CAS 17370-41-1)
- Bupropion Impurity 72 (CAS 102141-11-7)
- Selexipag Impurity 30 (CAS 1157086-87-7)
- 3-Bromo-2,6-dichlorobenzaldehyde (CAS 1254701-24-0)
- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(3,5-dimethylphenyl)acetic acid (CAS 2350338-07-5)
- 5-Bromo-2-(dimethylamino)nicotinonitrile (CAS 1346544-02-2)
- Bis(dicyclohexylphosphine)methane (CAS 137349-65-6)
- 2-oxaspiro[4.5]decane-1,3-dione (CAS 6051-25-8)
- (1R)-1-[3-(difluoromethoxy)phenyl]ethan-1-ol (CAS 1315378-60-9)
- Semaglutide Impurity 166 (CAS 1395881-03-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com