Erlotinib-d6 HCl CAS 1189953-78-3
| CAS No. | 1189953-78-3 |
| Molecular Formula | - |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Erlotinib-d6 HCl (CAS 1189953-78-3) is a high-purity analytical reference standard with the molecular formula C22H17D6N3O4HCl and a molecular weight of 435.94 g/mol.
Structurally, Erlotinib-d6 HCl (C22H17D6N3O4HCl) contains deuterium isotope labeling, a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 435.94 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H17D6N3O4 HCl |
| Molecular Weight | 435.94 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Erlotinib Standards
- Erlotinib Impurity 97 (CAS 1012057-39-4)
- Erlotinib Impurity 93 (CAS 1058132-82-3)
- Erlotinib impurity 136 (CAS 1058651-74-3)
- Erlotinib D4 (CAS 1130852-41-3)
- Erlotinib Impurity 123 (CAS 1145671-36-8)
- Erlotinib Hydrochloride Impurity 3 (CAS 1145671-52-8)
- Erlotinib Impurity 51 (CAS 115665-66-2)
- Erlotinib 13C6 Hydrochloride (CAS 1210610-07-3)
Recommended Standards
- 2-Methyl-4-((tetrahydro-2H-pyran-2-yl)oxy)-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde (CAS 1265359-19-0)
- 0499AD 1185303-15-4 4-(4-Ethoxyphenoxy)piperidine hydrochloride C13H20ClNO2 (CAS 1185303-15-4)
- 2-(1H-benzo[d]imidazol-2-yl)-1-(4-chlorophenyl)ethan-1-amine dihydrochloride (CAS 1179368-97-8)
- 2-Hydrazinylisonicotinohydrazide (CAS 89465-51-0)
- 2-(2-Methoxyethyl)-1,3-benzoxazol-5-amine (CAS 1248403-78-2)
- 1-(2,4-Dihydroxyphenyl)-2-phenoxyethan-1-one (CAS 73014-19-4)
- 1-[[[butyl(dimethyl)silyl]amino]-dimethylsilyl]butane (CAS 82356-80-7)
- Dimethyl (2R,3S)-piperidine-2,3-dicarboxylate (CAS 149880-78-4)
- 5-Bromo-1,2,3-trimethylbenzene (CAS 32591-43-8)
- Semaglutide Impurity 155 (x TFA Salt) (CAS CATO-C4X-2226155)
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