5-Chloro-1H-imidazo[4,5-b]pyrazine CAS 1196151-76-4
| CAS No. | 1196151-76-4 |
| Molecular Formula | C5H3ClN4 |
| Molecular Weight | 154.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5-Chloro-1H-imidazo[4,5-b]pyrazine (CAS 1196151-76-4), molecular formula C5H3ClN4 and molecular weight 154.56 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrile group, chlorine substitution, 5-Chloro-1H-imidazo[4,5-b]pyrazine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 154.56 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H3ClN4 |
| Molecular Weight | 154.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- 3-chloro-[1,2,4]triazolo[4,3-a]pyrimidine (CAS 1020036-31-0)
- 4-Chloro-1H-imidazo[4,5-d]pyridazine (CAS 1083181-53-6)
- 6-Chloro-7H-purine (CAS 111055-92-6)
- 7-Chloro-[1,2,4]triazolo[1,5-c]pyrimidine (CAS 1159811-23-0)
- 5-Chloro-1H-pyrazolo[3,4-b]pyrazine (CAS 116527-52-7)
- 6-Chloro-3H-[1,2,3]triazolo[4,5-c]pyridine (CAS 120641-09-0)
- 8-Chloro-[1,2,4]triazolo[4,3-c]pyrimidine (CAS 1208083-81-1)
- 6-Chloro-1H-pyrazolo[3,4-b]pyrazine (CAS 1260664-81-0)
Recommended Standards
- 2-Bromo-3,5-dichloropyrazine (CAS 1206249-40-2)
- 1246816-87-4 6-Chloropurine-13C2,15N (CAS 1246816-87-4)
- 6-Chlorooxazolo[5,4-b]pyridine (CAS 886373-58-6)
- 3-Chloro-1h-pyrazolo[3,4-b]pyrazine (CAS 1260773-79-2)
- 3-(Diethylamino)phenylboronic acid (CAS 186086-34-0)
- 2-Amino-5-oxo-5H-chromeno[2,3-b]pyridine-3-carbonitrile (CAS 61424-81-5)
- 1-Iodo-3-nitro-2-(trifluoromethoxy)benzene (CAS 1803738-58-0)
- 4-Iodohexahydro-2H-cyclopenta[b]furan-2,5-diol (CAS 62003-50-3)
- 4-methoxy-5-nitro-indoline (CAS 909556-12-3)
- N-(2-Hydroxyethyl)-N-methylperfluorohexanesulfonamide (CAS 68555-75-9)
- imidazo[1,2-a]pyridin-2-ylmethanol hydrochloride (CAS 82090-50-4)
- 3346-23-4 4-quinolinecarboxylic acid, 2-hydroxy-6-methyl- AR-1G4592 (CAS 3346-23-4)
- (3-(tert-Butoxy)-5-cyclopropoxypyridin-4-yl)methanamine (CAS 1243475-84-4)
- Gastric Inhibitory Polypeptide (3-42) (human) trifluoroacetate salt (CAS 1802086-25-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com