Erythromycin Impurity N8 CAS 119665-78-0
| CAS No. | 119665-78-0 |
| Molecular Formula | C48H94N2O14Si2 |
| Molecular Weight | 979.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Erythromycin Impurity N8 (C48H94N2O14Si2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 979.44 g/mol, it falls into the high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Erythromycin Impurity N8 (CAS 119665-78-0) is a certified pharmaceutical impurity reference standard with the molecular formula C48H94N2O14Si2 and a molecular weight of 979.44 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C48H94N2O14Si2 |
| Molecular Weight | 979.44 g/mol |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 2 |
Related Erythromycin Standards
- Erythromycin Compound M3 (CAS 119665-62-2)
- Erythromycin impurity 63 (CAS CATO-C4X-100163)
- Erythromycin Ethylsuccinate-13C-d3 (CAS 1264-62-6 (non-labelled))
- Erythromycin Ethylsuccinate (CAS 41342-53-4)
- Erythromycin Ethyl Succinate (CAS 1264-62-6)
- Erythromycin ethylsuccinate Impurity 52 (CAS CATO-C4X-100152)
- Erythromycin Propionate (CAS 134-36-1)
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Recommended Standards
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