2-Chloro-N-(2-(isopropylsulfonyl)phenyl)-5-(trifluoromethyl)pyrimidin-4-amine CAS 1197956-09-4

Purity 97%+In StockPharmaceutical Standards
CAS No.1197956-09-4
Molecular FormulaC14H13ClF3N3O2S
Molecular Weight379.79 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Chloro-N-(2-(isopropylsulfonyl)phenyl)-5-(trifluoromethyl)pyrimidin-4-amine CAS 1197956-09-4 chemical structure

Description

As a certified reference material (CRM), 2-Chloro-N-(2-(isopropylsulfonyl)phenyl)-5-(trifluoromethyl)pyrimidin-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

2-Chloro-N-(2-(isopropylsulfonyl)phenyl)-5-(trifluoromethyl)pyrimidin-4-amine (CAS 1197956-09-4), molecular formula C14H13ClF3N3O2S and molecular weight 379.79 g/mol, is a CATO reference standard with documented purity and traceability.

2-Chloro-N-(2-(isopropylsulfonyl)phenyl)-5-(trifluoromethyl)pyrimidin-4-amine (C14H13ClF3N3O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC14H13ClF3N3O2S
Molecular Weight379.79 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Halogen ContentF/Cl-containing
Nitrogen Atoms3
Sulfur Atoms1

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