Sofosbuvir Impurity 123 CAS 119804-96-5
| CAS No. | 119804-96-5 |
| Molecular Formula | C10H13N3O4 |
| Molecular Weight | 239.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Sofosbuvir Impurity 123 (CAS 119804-96-5, C10H13N3O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Sofosbuvir Impurity 123 (C10H13N3O4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Sofosbuvir Impurity 123 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H13N3O4 |
| Molecular Weight | 239.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 3 |
Related Sofosbuvir Standards
- Sofosbuvir Impurity 106 (CAS 119410-95-6)
- Sofosbuvir Impurity 54 (CAS 16731-31-0)
- Sofosbuvir Impurity 110 (CAS 51496-03-8)
- Sofosbuvir Impurity 16 (CAS 817204-33-4)
- Sofosbuvir Impurity 12 (CAS 2041584-99-8)
- Sofosbuvir Impurity 13 (CAS CATO-C4X-105213)
- Sofosbuvir Impurity 14 (CAS CATO-C4X-105214)
- Sofosbuvir Impurity 15 (CAS CATO-C4X-105215)
Recommended Standards
- 3-(4-Nitrophenyl)imidazo[1,2-a]pyridine (CAS 119690-43-6)
- 3-(Pyridin-2-yl)quinazoline-2,4(1H,3H)-dione (CAS 1217-26-1)
- 2-Amino-3-hydroxyanthraquinone (CAS 117-77-1)
- 1-Bromoundecane-1,1,2,2-d4 (CAS 1219802-82-0)
- Ixazomib Impurity 66 (CAS 50-38-4)
- Ambroxol Impurity 34 HCl (CAS CATO-C4X-108534)
- Vigabatrin Impurity 7 (CAS CATO-C4X-11967)
- 5-((Ethylthio)methyl)pyrimidin-2-amine (CAS 37795-59-8)
- 1,2-Di(naphthalen-2-yl)ethane-1,2-dione (CAS 29574-57-0)
- 1,2-Bis[(2R,5R)-2,5-dimethylphospholano]benzene(cyclooctadiene)rhodium(I) trifluoromethanesulfonate (CAS 187682-63-9)
- 3-Hydroxy-2-phenylisoindolin-1-one (CAS 18167-15-2)
- Maltose Heptasulfate Ester (CAS CATO-C3D-262595)
- 6-Bromo-3-methyl-2-(thiophen-2-yl)quinoline-4-carboxylic acid (CAS 354537-98-7)
- Insulin Degludec Impurity 11 (CAS CATO-C4X-215711)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com