Ixazomib Impurity 66 CAS 50-38-4
| CAS No. | 50-38-4 |
| Molecular Formula | C7H2Cl4O2 |
| Molecular Weight | 259.90 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Ixazomib Impurity 66 (CAS 50-38-4), a pharmacopoeial impurity reference standard (molecular formula C7H2Cl4O2, MW 259.90 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Ixazomib Impurity 66 (C7H2Cl4O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Ixazomib Impurity 66 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H2Cl4O2 |
| Molecular Weight | 259.90 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
Related Ixazomib Standards
- Ixazomib Impurity 65 (CAS 50-74-8)
- Ixazomib Impurity 45 (CAS CATO-C4X-126745)
- Ixazomib Impurity 10 (CAS 667403-46-5)
- Ixazomib Impurity 9 (CAS 1378314-08-9)
- Ixazomib Impurity 80 (CAS CATO-C4X-126780)
- Ixazomib Impurity 61 (CAS CATO-C4X-126761)
- Ixazomib Impurity 69 (CAS 121-48-2)
- Ixazomib Impurity 21 (CAS CATO-C4X-126721)
Recommended Standards
- 2,3-Dibromopentanoic acid (CAS 139185-84-5)
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- 2,5-Dibromopentanoic Acid (CAS 1450-81-3)
- 2-Fluoro-5-(trimethylstannyl)pyridine (CAS 660847-68-7)
- Dequalinium impurity 35 (CAS CATO-C4X-193635)
- Emtricitabine Int.Ph Impurity A (CAS CATO-C4X-123238)
- Gefitinib Impurity 34 (CAS 194423-17-1)
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- 2,4-Dichloro-1,8-naphthyridine (CAS 59514-89-5)
- (S)-1-(Benzo[d]thiazol-2-yl)ethan-1-ol (CAS 1059697-82-3)
- (S)-2-Amino-N-isopropyl-3-methyl-N-(2-oxo-2-(thiazol-2-yl)ethyl)butanamide (CAS 1354010-79-9)
- Ethyl 3-fluoro-5-iodobenzoate (CAS 850864-48-1)
- N-[6-Amino-1,2,3,4-tetrahydro-1-(2-methylpropyl)-2,4-dioxo-5-pyrimidinyl]-4-chloro-N-(2-methoxyethyl)butanamide (CAS 730949-94-7)
- Semaglutide Sodium Salt (CAS CATO-C4X-222620)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com