Carvedilol impurity 9 CAS 1198090-71-9
| CAS No. | 1198090-71-9 |
| Molecular Formula | C18H17NO3 |
| Molecular Weight | 295.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Carvedilol impurity 9 (C18H17NO3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 295.33 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Carvedilol impurity 9 (CAS 1198090-71-9, C18H17NO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H17NO3 |
| Molecular Weight | 295.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 1 |
Related Carvedilol Standards
- Carvedilol Impurity 4 (CAS 26646-63-9)
- Carvedilol Impurity 35 (CAS 1187921-93-2)
- Carvedilol Impurity 21 (CAS 553-45-7)
- Carvedilol Impurity 22 (CAS 3258-70-6)
- Carvedilol impurity 17 (CAS 123119-89-1)
- Carvedilol Impurity 4 (CAS 72955-96-5)
- Carvedilol USP Related Compound D (CAS 51997-51-4)
- Carvedilol O-Desmethyl Impurity (CAS 72956-44-6)
Recommended Standards
- Atenolol Impurity 18 (CAS 134720-04-0)
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- Doxofylline Impurity 43 (CAS CATO-C4X-151343)
- Docetaxel Impurity 66 (CAS 158830-39-8)
- Pirfenidone Impurity 7 (CAS 501935-40-6)
- Oxiracetam Impurity 1 (CAS 77191-37-8)
- Vonoprazan Impurity C295 (CAS 928325-68-2)
- 1,1,1-Trifluoro-3-((3-(trifluoromethyl)benzyl)amino)propan-2-ol (CAS 478068-12-1)
- N-methoxy-N-methyltetrahydrofuran-3-carboxamide (CAS 766539-67-7)
- N-(2-bromo-5-methylphenyl)acetamide (CAS 126759-48-6)
- 4-((3-(Trifluoromethyl)pyridin-2-yl)oxy)benzenesulfonamide (CAS 874839-24-4)
- 4,4',4'',4'''-Methanetetrayltetrabenzenesulfonic acid hydrate (CAS 1042058-12-7)
- 5-(4-Chlorobenzoyl)-2-methylpyridine (CAS 1187168-62-2)
- Semaglutide Impurity 16 (CAS CATO-C4X-222616)
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