Carvedilol Impurity 35 CAS 1187921-93-2
| CAS No. | 1187921-93-2 |
| Molecular Formula | C15H14ClNO2 |
| Molecular Weight | 275.73 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Carvedilol Impurity 35.
CATO supplies Carvedilol Impurity 35 (CAS 1187921-93-2), a pharmacopoeial impurity reference standard (molecular formula C15H14ClNO2, MW 275.73 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Carvedilol Impurity 35 (C15H14ClNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Carvedilol Impurity 35 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H14ClNO2 |
| Molecular Weight | 275.73 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Carvedilol Standards
- Carvedilol Impurity 21 (CAS 553-45-7)
- Carvedilol impurity 17 (CAS 123119-89-1)
- Carvedilol Impurity 4 (CAS 72955-96-5)
- Carvedilol impurity 9 (CAS 1198090-71-9)
- Carvedilol Impurity 4 (CAS 26646-63-9)
- Carvedilol USP Related Compound D (CAS 51997-51-4)
- Carvedilol Impurity 22 (CAS 3258-70-6)
- Carvedilol Impurity 24 (CAS 42988-85-2)
Recommended Standards
- N-Allyl-5-(4-chlorophenyl)-2-methylfuran-3-carboxamide (CAS 941238-50-2)
- Bezafibrate EP Impurity A (CAS 41859-57-8)
- N-allyl-4-chloro-1-(p-tolyl)-1H-pyrazole-5-carboxamide (CAS 318949-26-7)
- Bezafibrate Impurity 8 (CAS CATO-C4X-20178)
- Paliperidone Impurity 48 (CAS 181525-38-2)
- Piperazine Impurity 1 (CAS 37652-50-9)
- Troxerutin Impurity 5 (CAS 125092-04-8)
- 2,5-Diisopropylthiophen-3-amine hydrochloride (CAS 2567556-28-7)
- 1-(2,2-Difluoroethyl)piperidin-3-one (CAS 150-85-7)
- 1-(4-methanesulfonyl-3-methoxyphenyl)ethan-1-one (CAS 1221723-67-6)
- (4S)-2,5-diazabicyclo[2.2.1]Heptane-1-carboxylic acid (CAS 1902173-17-4)
- Isoprenaline Impurity 8 (CAS CATO-C4X-27758)
- 2-Hydroxy-N-(3-(trifluoromethyl)-phenyl)quinoline-5-carboxamide (CAS 1624262-32-3)
- Insulin Degludec Impurity 24 (CAS CATO-C4X-215724)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com