2,2,3,3-Tetrafluoro-2,3-dihydro-1,4-benzodioxin-5-amine CAS 119895-70-4

Purity 97%+In StockPharmaceutical Standards
CAS No.119895-70-4
Molecular FormulaC8H5F4NO2
Molecular Weight223.12 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2,2,3,3-Tetrafluoro-2,3-dihydro-1,4-benzodioxin-5-amine CAS 119895-70-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 223.12 g/mol gives 2,2,3,3-Tetrafluoro-2,3-dihydro-1,4-benzodioxin-5-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 2,2,3,3-Tetrafluoro-2,3-dihydro-1,4-benzodioxin-5-amine (CAS 119895-70-4), a certified reference material (molecular formula C8H5F4NO2, MW 223.12 g/mol) for analytical method development and quality control.

2,2,3,3-Tetrafluoro-2,3-dihydro-1,4-benzodioxin-5-amine (C8H5F4NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2,2,3,3-Tetrafluoro-2,3-dihydro-1,4-benzodioxin-5-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H5F4NO2
Molecular Weight223.12 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentF-containing
Nitrogen Atoms1

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