2,2,3,3-Tetrafluoro-2,3-dihydrobenzo[b][1,4]dioxin-6-ol CAS 103467-50-1

Purity 97%+In StockPharmaceutical Standards
CAS No.103467-50-1
Molecular FormulaC8H4F4O3
Molecular Weight224.11 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2,2,3,3-Tetrafluoro-2,3-dihydrobenzo[b][1,4]dioxin-6-ol CAS 103467-50-1 chemical structure

Description

The occurrence of 2,2,3,3-Tetrafluoro-2,3-dihydrobenzo[b][1,4]dioxin-6-ol is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2,2,3,3-Tetrafluoro-2,3-dihydrobenzo[b][1,4]dioxin-6-ol (CAS 103467-50-1), molecular formula C8H4F4O3 and molecular weight 224.11 g/mol, is a CATO reference standard with documented purity and traceability.

Based on its molecular formula C8H4F4O3, 2,2,3,3-Tetrafluoro-2,3-dihydrobenzo[b][1,4]dioxin-6-ol contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 224.11 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H4F4O3
Molecular Weight224.11 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1986
Halogen ContentF-containing

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