2,4,5-Trifluoro-1H-imidazole-1-carbaldehyde CAS 120047-74-7
| CAS No. | 120047-74-7 |
| Molecular Formula | C4HF3N2O |
| Molecular Weight | 150.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2,4,5-Trifluoro-1H-imidazole-1-carbaldehyde.
2,4,5-Trifluoro-1H-imidazole-1-carbaldehyde (CAS 120047-74-7) is a high-purity analytical reference standard with the molecular formula C4HF3N2O and a molecular weight of 150.06 g/mol.
The molecular framework of 2,4,5-Trifluoro-1H-imidazole-1-carbaldehyde (C4HF3N2O) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4HF3N2O |
| Molecular Weight | 150.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Trifluoro Standards
- 3,4,5-Trifluoro-1H-pyrazole-1-carbaldehyde (CAS 120047-73-6)
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Recommended Standards
- 4,5,6-Trifluoropyrimidin-2(1H)-one (CAS 173994-36-0)
- 2,2,3,3,3-Pentafluoro-1-propanol (CAS 422-05-9)
- 1,2,3,5-Tetrafluorobenzene (CAS 2367-82-0)
- Isoflurane EP Impurity B (CAS 1885-48-9)
- 4-(Azetidinomethyl)phenyl cyclopentyl ketone (CAS 898757-14-7)
- (R)-1-(tert-Butoxycarbonyl)-2-propylpyrrolidine-2-carboxylic acid (CAS 706806-57-7)
- N,4-Dimethyl-1H-imidazole-2-carboxamide (CAS 87864-88-8)
- Metoclopramide impurity 131 (CAS 40080-43-1)
- tert-butyl 2-((((2,4-dichloropyrimidin-5-yl)methyl)amino)methyl)piperidine-1-carboxylate (CAS 1420880-08-5)
- (E)-5-(4-(3,5-dimethyl-4-nitrostyryl)benzamido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid hydrate (CAS 1160555-05-4)
- N-(4-(1,1-Dioxidoisothiazolidin-2-yl)phenyl)-4-methylbenzamide (CAS 941974-63-6)
- Ribavirin EP Impurity B (CAS 57198-02-4)
- N-(2,4-dimethoxyphenyl)-2-(piperazin-1-yl)acetamide (CAS 946666-19-9)
- Semaglutide Impurity 11 (CAS CATO-C4X-222611)
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