1-[4-(Trifluoromethoxy)phenyl]cyclopropanamine CAS 1200798-12-4
| CAS No. | 1200798-12-4 |
| Molecular Formula | C10H10F3NO |
| Molecular Weight | 217.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-[4-(Trifluoromethoxy)phenyl]cyclopropanamine.
CATO supplies 1-[4-(Trifluoromethoxy)phenyl]cyclopropanamine (CAS 1200798-12-4), a certified reference material (molecular formula C10H10F3NO, MW 217.19 g/mol) for analytical method development and quality control.
The molecular framework of 1-[4-(Trifluoromethoxy)phenyl]cyclopropanamine (C10H10F3NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H10F3NO |
| Molecular Weight | 217.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethoxy Standards
- 2-[4-(Trifluoromethoxy)phenyl]cyclopropan-1-amine (CAS 1001316-74-0)
- 4-(Trifluoromethoxy)-2,3-dihydro-1H-inden-1-amine (CAS 1083090-92-9)
- 2-[2-(Trifluoromethoxy)phenyl]cyclopropan-1-amine (CAS 1157555-15-1)
- 5-(Trifluoromethoxy)-2,3-dihydro-1H-inden-1-amine (CAS 1211588-19-0)
- (R)-6-(trifluoromethoxy)-2,3-dihydro-1H-inden-1-amine (CAS 1213013-99-0)
- (S)-6-(trifluoromethoxy)-2,3-dihydro-1H-inden-1-amine (CAS 1213359-83-1)
- 6-(Trifluoromethoxy)-2,3-dihydro-1H-inden-1-amine (CAS 1248369-60-9)
- (R)-4-(trifluoromethoxy)-2,3-dihydro-1H-inden-1-amine (CAS 1259842-41-5)
Recommended Standards
- 2-Methyl-7-(trifluoromethyl)-3,4-dihydro-2H-1,4-benzoxazine (CAS 1195534-16-7)
- 3-(3-(Trifluoromethyl)-1h-pyrazol-1-yl)pentanenitrile (CAS 1169970-91-5)
- 2-((2,5-Difluorophenyl)sulfonyl)acetonitrile (CAS 1153970-94-5)
- (R)-7-(Trifluoromethyl)chroman-4-amine (CAS 1213657-96-5)
- 4-(2,2-difluoroethyl)-3,4-dihydro-2H-1,4-benzothiazin-6-amine hydrochloride (CAS 1803587-56-5)
- 1-((4-Bromophenyl)sulfonyl)-4-methylpiperazine (CAS 837-12-7)
- tert-Butyl 8-oxo-5-azaspiro[3.4]octane-5-carboxylate (CAS 1955539-76-0)
- 3-(Trifluoromethyl)pyrrolidine-2-carboxylic acid (CAS 1516757-19-9)
- 7-Bromo-2,3-dihydrobenzo[b][1,4]dioxin-6-ol (CAS 1216307-76-4)
- 4-Bromo-5-chloropicolinic acid (CAS 1256822-21-5)
- 3’,5’-Bis(trifluoromethyl)propiophenone (CAS 85068-34-4)
- 5-Cyclopentyl-1H-pyrazole-3-carboxylic acid (CAS 521300-21-0)
- 4,6-Dichloro-2-(methylthio)-5-nitro-pyrimidine (CAS 1979-96-0)
- Semaglutide impurity 72 (CAS CATO-C4X-222672)
Why CATO?
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