2-Iodo-4-methoxybenzoyl chloride CAS 1201221-65-9
| CAS No. | 1201221-65-9 |
| Molecular Formula | C8H6ClIO2 |
| Molecular Weight | 296.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Iodo-4-methoxybenzoyl chloride (C8H6ClIO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/iodine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
2-Iodo-4-methoxybenzoyl chloride (CAS 1201221-65-9), molecular formula C8H6ClIO2 and molecular weight 296.49 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H6ClIO2 |
| Molecular Weight | 296.49 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl/I-containing |
Related Iodo Standards
- 2-Iodo-3-methoxybenzoyl chloride (CAS 121404-82-8)
- 4-Iodo-3-methoxybenzoyl chloride (CAS 1231960-83-0)
- 2-Iodo-2'-methyl-1,1'-biphenyl (CAS 39655-09-9)
- Methyl 4-iodo-2,5-dimethylthiophene-3-carboxylate (CAS 859492-79-8)
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- Desmethyl-VS-5584 (CAS 1246535-95-4)
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