(4-Chloro-2-fluorophenyl)(cyclopropyl)methanol CAS 1202774-93-3
| CAS No. | 1202774-93-3 |
| Molecular Formula | C10H10ClFO |
| Molecular Weight | 200.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies (4-Chloro-2-fluorophenyl)(cyclopropyl)methanol (CAS 1202774-93-3), a certified reference material (molecular formula C10H10ClFO, MW 200.64 g/mol) for analytical method development and quality control.
The molecular framework of (4-Chloro-2-fluorophenyl)(cyclopropyl)methanol (C10H10ClFO) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H10ClFO |
| Molecular Weight | 200.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
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Recommended Standards
- 3-Chlorosulfonyl-butyric acid methyl ester (CAS 1154388-34-7)
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- 2-Chloro-5-fluoro-3-(pyrrolidin-2-yl)pyridine (CAS 1270360-19-4)
- 2-Fluoro-4-(2-thienyl)aniline (CAS 893737-94-5)
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- 4-Iodoquinazoline (CAS 630067-18-4)
- Methyl 2-(o-tolyl)pyrimidine-5-carboxylate (CAS 1263059-48-8)
- 4-(2-Chloro-4-(4-chlorophenoxy)phenyl)thiazol-2-amine (CAS 338756-39-1)
- 4-(Benzyloxy)-3-methylbenzofuran-2-carboxylic acid (CAS 193738-27-1)
- 1-Bromo-4-fluoroisoquinoline (CAS 1421517-86-3)
- 1-Cyclopropyl-1-(4-methoxyphenyl)ethan-1-ol (CAS 62586-86-1)
- Heptanoic-d13 Acid (CAS 130348-93-5)
- D-[His]1-Semaglutide X TFA salt (CAS CATO-CPTD788634)
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