BKM120 CAS 1202777-78-3
| CAS No. | 1202777-78-3 |
| Molecular Formula | C18H21F3N6O2 |
| Molecular Weight | 410.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including BKM120.
CATO supplies BKM120 (CAS 1202777-78-3), a certified reference material (molecular formula C18H21F3N6O2, MW 410.39 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, BKM120 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 410.39 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), BKM120 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H21F3N6O2 |
| Molecular Weight | 410.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
Recommended Standards
- Podophyllotoxin Impurity N2 (CAS 42123-27-3)
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- Vericiguat impurity 53 (CAS CATO-C4X-289653)
- 1-(Furan-2-ylmethyl)-5-oxo-N-(2-propoxy-5-(trifluoromethyl)phenyl)pyrrolidine-3-carboxamide (CAS 870760-17-1)
- N-(4-amino-2-chlorophenyl)isonicotinamide (CAS 926231-18-7)
- 4-Fluoro-2-methoxy-N-methylaniline, HCl (CAS 1215205-84-7)
- 1,6-Dihydropyrrolo[2,3-b]pyrrole-2-carboxylic acid (CAS 1783528-37-9)
- 3-(Thiophen-2-yl)azetidin-3-ol (CAS 1515760-41-4)
- 4-(1-methyl-1-phenylethyl)phenyl 3-piperidinylether 946681-21-6 (CAS 946681-21-6)
- (2-[(2,4-Difluorophenyl)methoxy]phenyl)boranediol (CAS 1335234-26-8)
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- 1-(2-Methylphenyl)-1H-imidazole-2-thiol (CAS 25372-14-9)
- Tert-butyl 2-(3-chlorophenyl)pyrrolidine-1-carboxylate (CAS 1467949-27-4)
- Neuropeptide K (human, porcine, rat) trifluoroacetate salt (CAS 96827-05-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com