2-(3-(((Tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-1-yl)-3-iodopyridine CAS 1203499-01-7
| CAS No. | 1203499-01-7 |
| Molecular Formula | C16H27IN2OSi |
| Molecular Weight | 418.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-(3-(((Tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-1-yl)-3-iodopyridine (C16H27IN2OSi) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
2-(3-(((Tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-1-yl)-3-iodopyridine (CAS 1203499-01-7) is a high-purity analytical reference standard with the molecular formula C16H27IN2OSi and a molecular weight of 418.39 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(3-(((Tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-1-yl)-3-iodopyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H27IN2OSi |
| Molecular Weight | 418.39 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 2 |
Related Tert Standards
- 4-(3-(((Tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-1-yl)-3-iodopyridine (CAS 1203498-95-6)
- 6-((3-(((Tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-1-yl)methyl)-2-(trimethylsilyl)furo[3,2-b]pyridine (CAS 1188993-09-0)
- (4-((4-((Tert-butyldimethylsilyl)oxy)piperidin-1-yl)sulfonyl)-2-fluorophenyl)boronic acid (CAS 1704096-28-5)
- 2-(((tert-Butyldimethylsilyl)oxy)methyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridine (CAS 2760431-07-8)
- 4-((3-(((Tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-1-yl)methyl)-2-chloro-3-(dimethoxymethyl)pyridine (CAS 1186311-19-2)
- 7-(((tert-Butyldimethylsilyl)oxy)methyl)-4-chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-7H-pyrrolo[2,3-d]pyrimidine (CAS 2114392-00-4)
- (4-(2-((tert-Butyldimethylsilyl)oxy)ethyl)-2-(trifluoromethyl)-5-(trimethylsilyl)thiophen-3-yl)methanol (CAS 2762829-25-2)
- 4-((Tert-butyldimethylsilyl)oxy)-7-fluoronaphthalen-2-yl trifluoromethanesulfonate (CAS 2449057-86-5)
Recommended Standards
- Kaempferol Tri-O-methoxymethyl Ether (CAS 143724-66-7)
- Centaureidin Impurity 1 (CAS 1176-88-1)
- 4-((5-Bromothiophen-2-yl)sulfonyl)-7-phenyl-1,4-thiazepane (CAS 1797347-94-4)
- 6-Carboxyhexylphosphocholine p-nitrophenyl ester (CAS 73785-43-0)
- 2-Chloro-N-(2-hydroxyethyl)propanamide (CAS 42275-81-0)
- 3-(3,4-Dimethoxy-2-methylphenyl)propanoic acid (CAS 1017073-96-9)
- tert-Butyl 3-(pyrazin-2-ylamino)pyrrolidine-1-carboxylate (CAS 1186298-86-1)
- 2-(4-Bromophenyl)dibenzo[f,h]quinoxaline (CAS 2044706-67-2)
- N1-(3-Fluorophenyl)-N2-(pyridin-2-ylmethyl)oxalamide (CAS 839685-84-6)
- Methyl 5-chloro-1-(2,4-dichlorobenzyl)-2-oxo-1,2-dihydropyridine-3-carboxylate (CAS 338977-75-6)
- 1-(2-Aminoethyl)-N-ethyl-1H-pyrazole-4-carboxamide (CAS 1707579-30-3)
- Methyl (3aR,5S,5aR,8aS,8bR)-2,2,7,7-tetramethyltetrahydro-5H-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-5-carboxylate (CAS 18524-41-9)
- 2-(4-(Pyridin-3-yl)thiazol-2-yl)acetonitrile (CAS 1016859-62-3)
- Semaglutide Impurity 131 (CAS 2618647-80-4)
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