6-(2,4-Difluorophenyl)-2-hydroxynicotinonitrile CAS 1204296-69-4
| CAS No. | 1204296-69-4 |
| Molecular Formula | C12H6F2N2O |
| Molecular Weight | 232.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-(2,4-Difluorophenyl)-2-hydroxynicotinonitrile (CAS 1204296-69-4), molecular formula C12H6F2N2O and molecular weight 232.19 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 6-(2,4-Difluorophenyl)-2-hydroxynicotinonitrile is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 232.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-(2,4-Difluorophenyl)-2-hydroxynicotinonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H6F2N2O |
| Molecular Weight | 232.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluorophenyl Standards
- 2-(2,4-Difluorophenyl)oxazolo[4,5-b]pyridine (CAS 52333-52-5)
- 2-(2,5-Difluorophenyl)oxazolo[4,5-b]pyridine (CAS 52333-66-1)
- 2-(2,6-Difluorophenyl)oxazolo[4,5-b]pyridine (CAS 52333-73-0)
- 3-(2,4-Difluorophenyl)-3H-[1,2,3]triazolo[4,5-b]pyridine (CAS 62051-90-5)
- 3-(2,5-Difluorophenyl)-3H-[1,2,3]triazolo[4,5-b]pyridine (CAS 62052-04-4)
- 3-(2,6-Difluorophenyl)-3H-[1,2,3]triazolo[4,5-b]pyridine (CAS 62052-06-6)
- 8-(2,3-difluorophenyl)-7H-purine (CAS 878287-57-1)
- (2,4-Difluorophenyl)(m-tolyl)methanone (CAS 1094311-95-1)
Recommended Standards
- 5-(2H-1,3-benzodioxol-5-yl)-1h-pyrazole-4-carboxylic acid (CAS 1152543-46-8)
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- 1-(1,3-Dioxaindan-5-yl)-1h-pyrazole-3-carboxylic acid (CAS 1152534-49-0)
- Methyl 3-(cyanomethyl)-2-oxo-2,3-dihydrobenzo[d]oxazole-5-carboxylate (CAS 1211502-70-3)
- 3-Nitrobenzenebutanoic Acid (CAS 1823-15-0)
- 1-(4-Aminobutyl)-1H-pyrrole-2,5-dione (CAS 945530-68-7)
- 2-{[(4-methylphenyl)methyl]sulfanyl}-4-(phenylsulfanyl)-5,6,7,8-tetrahydroquinazoline (CAS 343374-07-2)
- 5-Chloro-6-(2-methylpropoxy)pyridine-3-carboxylic acid (CAS 1008769-66-1)
- 4’-Amino-2’-hydroxyacetophenone (CAS 2476-29-1)
- 2-(2,2-difluorocyclopropoxy)ethanesulfonyl chloride (CAS 1989659-89-3)
- 1-(1-hydroxycyclohexyl)-3-(4-methoxyphenyl)propan-1-one 23936-11-0 (CAS 23936-11-0)
- 2-chloro-N-(4-chlorobenzyl)-N-methylacetamide (CAS 39086-65-2)
- 3-bromo-4-methylpyridin-2-amine (CAS 40073-38-9)
- Antistasin-Related Peptide (CAS 161561-46-2)
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